Recombinant Human CAT1 protein

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

CAT1 influences nitric oxide production by regulating arginine availability a substrate for nitric oxide synthase. By controlling amino acid imports it affects cellular signaling and metabolism. CAT1 does not function as part of a larger complex but interacts with other transporters to maintain cellular amino acid balance. CAT1's role extends to impacting cell proliferation as cationic amino acids are important for growing tissues.

Pathways

CAT1 has been implicated in the nitric oxide synthesis pathway where it contributes by sustaining intracellular arginine levels. This involvement is critical to vascular function and immune response regulation. CAT1 also participates in mTOR signaling by providing necessary amino acids like arginine which influence protein synthesis and cellular growth. In these pathways CAT1 connects with proteins such as mTOR and nitric oxide synthase assisting in integral cellular functions.