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Recombinant Human CD137 protein (Active) is a Human Fragment protein, in the 24 to 186 aa range, <= 0.005 EU/µg endotoxin level and suitable for SDS-PAGE, MS.
Alternative names=Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, ILA, CD137
- Purity
HPLC
- Endotoxin level
<= 0.005 EU/µg
- Tags
Tag free
- Applications
SDS-PAGE, MS
- Biologically active
Yes
- Actual molecular weight
17.3 kDa
- Sequence
L Q D P C S N C P A G T F C D N N R N Q I C S P C P P N S F S S A G G Q R T C D I C R Q C K G V F R T R K E C S S T S N A E C D C T P G F H C L G A G C S M C E Q D C K Q G Q E L T K K G C K D C C F G T F N D Q K R G I C R P W T N C S L D G K S V L V N G T K E R D V V C G P S P A D L S P G A S S V T P P A P A R E P G H S P Q
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
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Recombinant Human CD137 protein (Active) is a Human Fragment protein, in the 24 to 186 aa range, <= 0.005 EU/µg endotoxin level and suitable for SDS-PAGE, MS.
Alternative names=Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, ILA, CD137
Key facts
- Purity
HPLC
- Endotoxin level
<= 0.005 EU/µg
- Tags
Tag free
- Applications
SDS-PAGE, MS
- Biologically active
Yes
- Biological activity
Fully biologically active determined by the dose dependent inhibition of anti-4-1BB antibody mediated activation of genetically engineered Jurkat T cell coexpressing 4-1BB and a responsive reporter element in presence of FcgammaRIIb CHO-K1 cells.
ED50 is ≤ 126.7 ng/ml, corresponding to a specific activity of 7.9 x 103 units/mg.
- Predicted molecular weight
17.3 kDa
- Actual molecular weight
17.3 kDa
- Amino acids
24 to 186
- Sequence
L Q D P C S N C P A G T F C D N N R N Q I C S P C P P N S F S S A G G Q R T C D I C R Q C K G V F R T R K E C S S T S N A E C D C T P G F H C L G A G C S M C E Q D C K Q G Q E L T K K G C K D C C F G T F N D Q K R G I C R P W T N C S L D G K S V L V N G T K E R D V V C G P S P A D L S P G A S S V T P P A P A R E P G H S P Q
- Accession
- Q07011-1
- Protein length
Fragment
- Animal free
Yes
- Nature
Recombinant
- Species
Human
- Reconstitution
Reconstitute with phosphate buffered saline. Store lyophilized form at room temperature. Reconstitute, aliquot and store at -80°C for 12 months or +4°C for 1 week. Avoid repeated freeze-thaw. Lyophilized contents may appear as either a translucent film or a white power. This variance does not affect the quality of the product.
- Concentration
- Storage buffer
pH: 7.4
Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic
Specifications
- Form
Lyophilized
General info
- Function
Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
Ambient
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Product promise
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