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AB276481

Recombinant Human CD300a protein (His tag)

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Recombinant Human CD300a protein (His tag) is a Human Fragment protein, in the 1 to 178 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

CD300a, CMRF35H, IGSF12, HSPC083, CD300A, CMRF35-like molecule 8, CLM-8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor, CMRF35-H9, IgSF12, IRp60

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SDS-PAGE - Recombinant Human CD300a protein (His tag) (AB276481)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human CD300a protein (His tag) (AB276481)

SDS-PAGE analysis of ab276481

Key facts

Purity

>90% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q9UGN4

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

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Complementary Products

Primary Antibodies

AB243084

APC Anti-CD300a antibody [MEM-260]

Flow Cytometry - APC Anti-CD300a antibody [MEM-260] (AB243084)

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Assay Kits

AB317784

Human CD300a ELISA Kit

SimpleStep

Sandwich ELISA - Human CD300a ELISA Kit (AB317784)

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Primary Antibodies

AB98861

Anti-PBA1 antibody

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Proteins & Peptides

AB106870

Recombinant Human Calcium binding protein 7 (His tag N-Terminus)

SDS-PAGE - Recombinant Human Calcium binding protein 7 (His tag N-Terminus) (AB106870)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"linker":null,"sequence":"MWLPWALLLLWVPGCFALSKCRTVAGPVGGSLSVQCPYEKEHRTLNKYWCRPPQIFLCDKIVETKGSAGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPVVEVEVSVFPASTSMTPASITAAKTSTITTAFPPVSSTTLFAVGATHSASIQEETEEVVNSQ","proteinLength":"Fragment","predictedMolecularWeight":"18.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":178,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q9UGN4","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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Properties and storage information

Form
Lyophilized
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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General info

Function

Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed : 10746781, PubMed : 16339535, PubMed : 9701027). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed : 22043923).

Sequence similarities

Belongs to the CD300 family.

Post-translational modifications

Phosphorylated on tyrosine.. N-glycosylated.

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Product protocols

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Target data

Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed : 10746781, PubMed : 16339535, PubMed : 9701027). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed : 22043923).
See full target information CD300A
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Product promise

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