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AB269989

Recombinant Human CD32B protein (Tagged)

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Recombinant Human CD32B protein (Tagged) is a Human Fragment protein, in the 46 to 217 aa range, expressed in HEK 293 cells, with >90%, suitable for SDS-PAGE, WB.

View Alternative Names

CD32, FCG2, IGFR2, FCGR2B, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b

2 Images
Western blot - Recombinant Human CD32B protein (Tagged) (AB269989)
  • WB

Unknown

Western blot - Recombinant Human CD32B protein (Tagged) (AB269989)

Western blot analysis of ab269989.

All lanes:

Western blot - Recombinant Human CD32B protein (Tagged) (ab269989)

false

SDS-PAGE - Recombinant Human CD32B protein (Tagged) (AB269989)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human CD32B protein (Tagged) (AB269989)

SDS-PAGE analysis of 5 μg ab269989. 4-20% gel with Coomasie staining.

Key facts

Purity

>90% SDS-PAGE

Expression system

HEK 293 cells

Tags

Avi tag C-Terminus His tag C-Terminus

Applications

SDS-PAGE, WB

applications

Biologically active

No

Accession

P31994

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 20% Glycerol (glycerin, glycerine), 0.64% Sodium chloride, 0.13% Sodium phosphate, 0.02% Potassium chloride

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"sequence":"APPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAP","proteinLength":"Fragment","predictedMolecularWeight":"23 kDa","actualMolecularWeight":null,"aminoAcidEnd":217,"aminoAcidStart":46,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"P31994","tags":[{"tag":"Avi","terminus":"C-Terminus"},{"tag":"His","terminus":"C-Terminus"}]}]

Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Storage information
Avoid freeze / thaw cycle
False

Specifications

Form

Liquid

Additional notes

nan

General info

Function

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Post-translational modifications

Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.

Product protocols

Target data

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
See full target information FCGR2B

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