Recombinant Human CD32B protein (Biotin) (Avi tag C-Terminus + His tag C-Terminus)
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Recombinant Human CD32B protein (Biotin) (Avi tag C-Terminus + His tag C-Terminus) is a Human Fragment protein, in the 46 to 217 aa range, expressed in HEK 293 cells, with >90%, suitable for SDS-PAGE.
View Alternative Names
CD32, FCG2, IGFR2, FCGR2B, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human CD32B protein (Biotin) (Avi tag C-Terminus + His tag C-Terminus) (AB269994)
SDS-PAGE analysis of ab269994 (4 μg) on a 4-20% gel with Coomassie staining.
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Storage information
Specifications
Form
Liquid
General info
Function
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Post-translational modifications
Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.
Target data
Product promise
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