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Recombinant human CD45 protein is a Human Fragment protein, in the 604 to 1304 aa range, expressed in Baculovirus infected Sf9, with >90% purity and suitable for SDS-PAGE, WB, FuncS.
Alternative names=Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, T200, L-CA, PTPRC, CD45
- Purity
>90% SDS-PAGE
- Expression system
Baculovirus infected Sf9 cells
- Tags
Tag free
- Applications
SDS-PAGE, WB, FuncS
- Biologically active
Yes
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Application FuncS | Reactivity Reacts | Dilution info - | Notes - |
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Recombinant human CD45 protein is a Human Fragment protein, in the 604 to 1304 aa range, expressed in Baculovirus infected Sf9, with >90% purity and suitable for SDS-PAGE, WB, FuncS.
Alternative names=Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, T200, L-CA, PTPRC, CD45
Key facts
- Purity
>90% SDS-PAGE
- Expression system
Baculovirus infected Sf9 cells
- Tags
Tag free
- Applications
SDS-PAGE, WB, FuncS
- Biologically active
Yes
- Biological activity
The specific activity of ab94517 is 11,500 nmol phosphate released /min/mg
- Amino acids
604 to 1304
- Accession
- P08575-3
- Protein length
Fragment
- Animal free
No
- Nature
Recombinant
- Species
Human
- Concentration
- Storage buffer
pH: 7
Preservative: 1.02% Imidazole
Constituents: 25% Glycerol (glycerin, glycerine), 1.74% Sodium chloride, 1.045% MOPS, 0.00385% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.00174% PMSF
Specifications
- Form
Liquid
- Additional notes
>90% as determined by densitometry. Affinity purified.
General info
- Function
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
- Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Receptor class 1/6 subfamily.
- Post-translational modifications
Heavily N- and O-glycosylated.
Storage
- Shipped at conditions
Dry Ice
- Appropriate long-term storage conditions
-80°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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