JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB126928

Recombinant Human CDK3 protein (GST tag N-Terminus)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human CDK3 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 305 aa range, expressed in Baculovirus infected Sf9 cells, with >70%, suitable for SDS-PAGE.
1 Images
SDS-PAGE - Recombinant Human CDK3 protein (GST tag N-Terminus) (AB126928)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CDK3 protein (GST tag N-Terminus) (AB126928)

SDS-PAGE analysis of ab126928.

Key facts

Purity

>70% Densitometry

Affinity purified.

Expression system

Baculovirus infected Sf9 cells

Tags

GST tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q00526-1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.79% Tris HCl, 0.31% Glutathione, 0.0039% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

storage-buffer

style
left-column

Complementary Products

Proteins & Peptides

AB271456

Recombinant human CDK1 + Cyclin B1 protein (Active) (GST tag N-Terminus)

Functional Studies - Recombinant human CDK1 + Cyclin B1 protein (Active) (GST tag N-Terminus) (AB271456)

  • 0
  • 0
Proteins & Peptides

AB111646

Recombinant Human CDK2 protein (His tag C-Terminus)

SDS-PAGE - Recombinant Human CDK2 protein (His tag C-Terminus) (AB111646)

  • 0
  • 0
Proteins & Peptides

AB126920

Recombinant Human Cdk7 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human Cdk7 protein (GST tag N-Terminus) (AB126920)

  • 0
  • 0
Proteins & Peptides

AB268396

Recombinant human Cyclin E2 + CDK2 protein (Active) (GST tag N-Terminus)

Functional Studies - Recombinant human Cyclin E2 + CDK2 protein (Active) (AB268396)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"linker":null,"sequence":"","proteinLength":"Full Length","predictedMolecularWeight":"60 kDa","actualMolecularWeight":null,"aminoAcidEnd":305,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q00526","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

General info

Function

Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

style
left-column

Product protocols

style
left-column

Target data

Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
See full target information CDK3

Alternative Names

CDKN3, CDK3, Cyclin-dependent kinase 3, Cell division protein kinase 3
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com