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AB131695

Recombinant Human CDKL5 protein

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(2 Publications)

Recombinant Human CDKL5 protein is a Human Fragment protein, in the 1 to 498 aa range, expressed in Baculovirus infected Sf9 cells, with >90%, suitable for SDS-PAGE.

View Alternative Names

STK9, CDKL5, Cyclin-dependent kinase-like 5, Serine/threonine-protein kinase 9

1 Images
SDS-PAGE - Recombinant Human CDKL5 protein (AB131695)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CDKL5 protein (AB131695)

The purity of ab131695 was determined to be >90% by densitometry.

Key facts

Purity

>90% SDS-PAGE

Expression system

Baculovirus infected Sf9 cells

Tags

GST tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

O76039

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.79% Tris HCl, 0.31% Glutathione, 0.29% Sodium chloride, 0.005% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":"84 kDa","actualMolecularWeight":null,"aminoAcidEnd":498,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"O76039","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

Assessed by densitometry. Affinity purified.

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General info

Function

Mediates phosphorylation of MECP2 (PubMed : 15917271, PubMed : 16935860). May regulate ciliogenesis (PubMed : 29420175).

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Post-translational modifications

Autophosphorylated.

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Product protocols

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Target data

Mediates phosphorylation of MECP2 (PubMed : 15917271, PubMed : 16935860). May regulate ciliogenesis (PubMed : 29420175).
See full target information CDKL5
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 25: PubMed39201578

2024

Bacterial Production of CDKL5 Catalytic Domain: Insights in Aggregation, Internal Translation and Phosphorylation Patterns.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea Colarusso,Concetta Lauro,Luisa Canè,Flora Cozzolino,Maria Luisa Tutino

Microbial cell factories 21:211 PubMed36242022

2022

Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea Colarusso,Concetta Lauro,Marzia Calvanese,Ermenegilda Parrilli,Maria Luisa Tutino
View all publications
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