JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB162978

Recombinant Human CEP27 protein

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human CEP27 protein is a Human Full Length protein, in the 1 to 235 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

C15orf25, CEP27, HAUS2, HAUS augmin-like complex subunit 2, Centrosomal protein of 27 kDa, Cep27

1 Images
SDS-PAGE - Recombinant Human CEP27 protein (AB162978)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CEP27 protein (AB162978)

ab162978 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Q9NVX0

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"MAAANPWDPASAPNGAGLVLGHFIASGMVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":235,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9NVX0","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CEP27 also known as Centrosomal protein 27 or CECR2 is a protein that mechanically plays a role in centrosome function and cell cycle regulation. It has a molecular mass of approximately 28 kDa. Researchers have found CEP27 expression across various human tissues with notable levels in the brain and heart. This protein localizes in the centrosome an important cellular structure involved in microtubule organization particularly during cell division.
Biological function summary

CEP27 contributes to the maintenance of cell structure and integrity. It forms part of the centrosome complex which is essential for the proper organization of the spindle apparatus during mitosis. The coordination of CEP27 with other centrosomal proteins ensures the correct segregation of chromosomes fundamental for normal cell proliferation. Disruption of its function can lead to errors in chromosome distribution highlighting its role in genetic stability.

Pathways

Scientists have found CEP27 functions within the framework of the cell cycle regulation and mitotic spindle assembly pathways. Its interaction with proteins such as CEP192 and CEP350 reinforces its involvement in centrosome cohesion and microtubule anchoring processes. These pathways are essential for correct cell cycle progression and division indicating CEP27's critical role in cellular replication and organization.

Variations in CEP27 are associated with certain cancers including glioblastoma and breast cancer. Its interaction with proteins like NEK2 and Aurora kinase A both implicated in oncogenesis suggests that CEP27 influences tumorigenic pathways. Aberrations in expression or function may contribute to uncontrolled cell proliferation making CEP27 a potential target for therapeutic intervention in cancer research.
style
left-column

Specifications

Form

Liquid

style
left-column

General info

Function

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Sequence similarities

Belongs to the HAUS2 family.

Subcellular localisation

Cytoskeleton

style
left-column

Product protocols

style
left-column

Target data

Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
See full target information HAUS2
style
left-column
style
left-column
style
right-column

Complementary Products

Proteins & Peptides

AB159808

Recombinant Human ZAN protein

SDS-PAGE - Recombinant Human ZAN protein (AB159808)

  • 0
  • 0
Proteins & Peptides

AB159886

Recombinant Human ZP2 protein

SDS-PAGE - Recombinant Human ZP2 protein (AB159886)

  • 0
  • 0
Proteins & Peptides

AB163077

Recombinant Human VNN3 protein

SDS-PAGE - Recombinant Human VNN3 protein (AB163077)

  • 0
  • 0
Proteins & Peptides

AB162402

Recombinant Human Zinc finger protein 691

SDS-PAGE - Recombinant Human Zinc finger protein 691 (AB162402)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com