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AB162408

Recombinant Human CHREBP protein (GST tag N-Terminus)

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(1 Publication)

Recombinant Human CHREBP protein (GST tag N-Terminus) is a Human Fragment protein, in the 603 to 700 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

BHLHD14, MIO, WBSCR14, MLXIPL, Carbohydrate-responsive element-binding protein, ChREBP, Class D basic helix-loop-helix protein 14, MLX interactor, MLX-interacting protein-like, WS basic-helix-loop-helix leucine zipper protein, Williams-Beuren syndrome chromosomal region 14 protein, bHLHd14, WS-bHLH

1 Images
SDS-PAGE - Recombinant Human CHREBP protein (GST tag N-Terminus) (AB162408)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CHREBP protein (GST tag N-Terminus) (AB162408)

ab162408 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q9NP71

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Complementary Products

Secondary Antibodies

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Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Primary Antibodies

AB92809

Anti-CHREBP antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CHREBP antibody (AB92809)

  • 0
  • 1
Assay Kits

AB196985

Cholesterol Efflux Assay Kit (Cell-based)

Biochemical assay - Cholesterol Efflux Assay Kit (Cell-based) (AB196985)

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Proteins & Peptides

AB162883

Recombinant Human ELOVL2 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human ELOVL2 protein (GST tag N-Terminus) (AB162883)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYI","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":700,"aminoAcidStart":603,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9NP71","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Glucose-responsive transcription activator that regulates fatty acid synthesis and glycolysis. Key determinant of systemic insulin sensitivity and glucose homeostasis. Important for the expression of fatty acid synthetic enzymes, including PC/Pcx, APOC4/Acl, ACACA/Acc1 and FASN/Fas (By similarity). Important for glucose-induced expression of L-type pyruvate kinase/PKLR (By similarity). Binds to the canonical and non-canonical E box DNA sequences 5'-CACGTG-3' and 5'-CACGCG-3' (By similarity). May also act as a transcriptional repressor (By similarity).

Post-translational modifications

Phosphorylation at Ser-556 by AMPK inactivates the DNA-binding activity.

Subcellular localisation

Nucleus

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Product protocols

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Target data

Glucose-responsive transcription activator that regulates fatty acid synthesis and glycolysis. Key determinant of systemic insulin sensitivity and glucose homeostasis. Important for the expression of fatty acid synthetic enzymes, including PC/Pcx, APOC4/Acl, ACACA/Acc1 and FASN/Fas (By similarity). Important for glucose-induced expression of L-type pyruvate kinase/PKLR (By similarity). Binds to the canonical and non-canonical E box DNA sequences 5'-CACGTG-3' and 5'-CACGCG-3' (By similarity). May also act as a transcriptional repressor (By similarity).
See full target information MLXIPL
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Metabolites 13: PubMed36837888

2023

Luteolin-7-O-rutinoside Protects RIN-5F Cells from High-Glucose-Induced Toxicity, Improves Glucose Homeostasis in L6 Myotubes, and Prevents Onset of Type 2 Diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Pandurangan Subash-Babu,Sahar Abdulaziz AlSedairy,Manal Abdulaziz Binobead,Ali A Alshatwi
View all publications
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Product promise

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