JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB276651

Recombinant Human CHRNB3 protein (His tag)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human CHRNB3 protein (His tag) is a Human Fragment protein, in the 1 to 232 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

Neuronal acetylcholine receptor subunit beta-3, CHRNB3

1 Images
SDS-PAGE - Recombinant Human CHRNB3 protein (His tag) (AB276651)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human CHRNB3 protein (His tag) (AB276651)

SDS-PAGE analysis of ab276651

Key facts

Purity

>90% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

His tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q05901

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 100% PBS

storage-buffer

style
left-column

Complementary Products

Proteins & Peptides

AB235737

Recombinant Human Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 protein (Tagged)

SDS-PAGE - Recombinant Human Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 protein (Tagged) (AB235737)

  • 0
  • 0
Secondary Antibodies

AB112771

Goat Anti-Bird IgY H&L

  • 0
  • 0
Primary Antibodies

AB236745

Anti-CHRNB3 antibody

Immunocytochemistry/ Immunofluorescence - Anti-CHRNB3 antibody (AB236745)

  • 0
  • 0
Proteins & Peptides

AB290100

Recombinant Human TNF Receptor II Protein (Active)

Premium Bioactive

Biological Activity - Recombinant Human TNF Receptor II Protein (Active) (AB290100)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"MLPDFMLVLIVLGIPSSATTGFNSIAENEDALLRHLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGTVVWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDLILINENVDRKDFFDNGEWEILNAKGMKGNRRDGVYSYPFITYSFVLRRL","proteinLength":"Fragment","predictedMolecularWeight":"25.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":232,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q05901","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

Specifications

Form

Lyophilized

style
left-column

General info

Function

Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators (PubMed : 11118490, PubMed : 16835356, PubMed : 35889515). Has an accessory rather than functional role and is only able to form functional nAChRs when co-assembled with another beta subunit (PubMed : 11118490, PubMed : 16835356). Participates in pentameric assemblies along with CHRNA3, CHRNA4, CHRNA6, CHRNB2 and CHRNB4 (PubMed : 11118490, PubMed : 16835356). Modulates receptor assembly and increases receptor sensitivity to nicotine when associated with CHRNB2, CHRNA4 and/or CHRNA6 as well as CHRNA3 and CHRNB4 (PubMed : 11118490, PubMed : 16835356). Seems to play a role in nicotine addiction (PubMed : 11118490, PubMed : 16835356).

Sequence similarities

Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-3/CHRNB3 sub-subfamily.

style
left-column

Product protocols

style
left-column

Target data

Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators (PubMed : 11118490, PubMed : 16835356, PubMed : 35889515). Has an accessory rather than functional role and is only able to form functional nAChRs when co-assembled with another beta subunit (PubMed : 11118490, PubMed : 16835356). Participates in pentameric assemblies along with CHRNA3, CHRNA4, CHRNA6, CHRNB2 and CHRNB4 (PubMed : 11118490, PubMed : 16835356). Modulates receptor assembly and increases receptor sensitivity to nicotine when associated with CHRNB2, CHRNA4 and/or CHRNA6 as well as CHRNA3 and CHRNB4 (PubMed : 11118490, PubMed : 16835356). Seems to play a role in nicotine addiction (PubMed : 11118490, PubMed : 16835356).
See full target information Neuronal acetylcholine receptor subunit beta-3
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com