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AB202186

Recombinant Human CLEC5A protein (denatured)

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Recombinant Human CLEC5A protein (denatured) is a Human Fragment protein, in the 28 to 188 aa range, expressed in Escherichia coli, with >80%, suitable for SDS-PAGE.

View Alternative Names

CLECSF5, MDL1, CLEC5A, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, MDL-1

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SDS-PAGE - Recombinant Human CLEC5A protein (denatured) (AB202186)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human CLEC5A protein (denatured) (AB202186)

15% SDS-PAGE analysis of ab202186 (3 μg).

Key facts

Purity

>80% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q9NY25

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.32% Tris HCl

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSPQIFNKSNDGFTTTRSYGTVSQIFGSSSPSPNGFITTRSYGTVCPKDWEFYQARCFFLSTSESSWNESRDFCKGKGSTLAIVNTPEKLKFLQDITDAEKYFIGLIYHREEKRWRWINNSVFNGNVTNQNQNFNCATIGLTKTFDAASCDISYRRICEKNAK","proteinLength":"Fragment","predictedMolecularWeight":"20.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":188,"aminoAcidStart":28,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9NY25","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab202186 was purified by conventional chromatography techniques

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General info

Function

Functions as a positive regulator of osteoclastogenesis (By similarity). Cell surface receptor that signals via TYROBP (PubMed : 10449773). Regulates inflammatory responses (By similarity).. (Microbial infection) Critical macrophage receptor for dengue virus serotypes 1-4 (PubMed : 18496526, PubMed : 21566123). The binding of dengue virus to CLEC5A triggers signaling through the phosphorylation of TYROBP (PubMed : 18496526). This interaction does not result in viral entry, but stimulates pro-inflammatory cytokine release (PubMed : 18496526).

Post-translational modifications

N-glycosylated. Contains sialic acid residues.

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Product protocols

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Target data

Functions as a positive regulator of osteoclastogenesis (By similarity). Cell surface receptor that signals via TYROBP (PubMed : 10449773). Regulates inflammatory responses (By similarity).. (Microbial infection) Critical macrophage receptor for dengue virus serotypes 1-4 (PubMed : 18496526, PubMed : 21566123). The binding of dengue virus to CLEC5A triggers signaling through the phosphorylation of TYROBP (PubMed : 18496526). This interaction does not result in viral entry, but stimulates pro-inflammatory cytokine release (PubMed : 18496526).
See full target information CLEC5A
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