Recombinant Human CLIC2 protein is a Human Full Length protein, in the 1 to 247 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
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Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M S G L R P G T Q V D P E I E L F V K A G S D G E S I G N C P F C Q R L F M I L W L K G V K F N V T T V D M T R K P E E L K D L A P G T N P P F L V Y N K E L K T D F I K I E E F L E Q T L A P P R Y P H L S P K Y K E S F D V G C N L F A K F S A Y I K N T Q K E A N K N F E K S L L K E F K R L D D Y L N T P L L D E I D P D S A E E P P V S R R L F L D G D Q L T L A D C S L L P K L N I I K V A A K K Y R D F D I P A E F S G V W R Y L H N A Y A R E E F T H T C P E D K E I E N T Y A N V A K Q K S
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application MS | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Displays weak glutathione peroxidase activity (Probable) (PubMed:25581026). Can insert into membranes and form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
Alternative names
Chloride intracellular channel protein 2, Glutaredoxin-like oxidoreductase CLIC2, Glutaredoxin-like peroxidase CLIC2, XAP121, CLIC2
Recommended products
Recombinant Human CLIC2 protein is a Human Full Length protein, in the 1 to 247 aa range, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, MS.
Key facts
- Purity
- >95% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE, MS
- Biologically active
- No
- Accession
- O15247-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 20% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.316% Tris HCl, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M S G L R P G T Q V D P E I E L F V K A G S D G E S I G N C P F C Q R L F M I L W L K G V K F N V T T V D M T R K P E E L K D L A P G T N P P F L V Y N K E L K T D F I K I E E F L E Q T L A P P R Y P H L S P K Y K E S F D V G C N L F A K F S A Y I K N T Q K E A N K N F E K S L L K E F K R L D D Y L N T P L L D E I D P D S A E E P P V S R R L F L D G D Q L T L A D C S L L P K L N I I K V A A K K Y R D F D I P A E F S G V W R Y L H N A Y A R E E F T H T C P E D K E I E N T Y A N V A K Q K S
- Accession
- O15247
- Protein length
- Full Length
- Predicted molecular weight
- 30.5 kDa
- Amino acids
- 1 to 247
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
ab106875 was purified using conventional chromatography.
General info
- Function
In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Displays weak glutathione peroxidase activity (Probable) (PubMed:25581026). Can insert into membranes and form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
- Sequence similarities
Belongs to the chloride channel CLIC family.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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1 product image
SDS-PAGE - Recombinant Human CLIC2 protein (ab106875)
15% SDS-PAGE analysis of 3 μg ab106875.
Downloads
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