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AB162692

Recombinant Human CLIC5 protein

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Recombinant Human CLIC5 protein is a Human Fragment protein, in the 91 to 190 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

Chloride intracellular channel protein 5, Glutaredoxin-like oxidoreductase CLIC5, CLIC5

1 Images
SDS-PAGE - Recombinant Human CLIC5 protein (AB162692)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CLIC5 protein (AB162692)

ab162692 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

Q9NZA1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"FLEETLTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLP","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":190,"aminoAcidStart":91,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9NZA1","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor (By similarity). Can insert into membranes and form non-selective ion channels almost equally permeable to Na(+), K(+) and Cl(-) (PubMed : 15184393, PubMed : 18028448). Required for normal hearing (PubMed : 24781754). It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed : 15184393, PubMed : 18028448, PubMed : 20335315). Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens (By similarity).

Sequence similarities

Belongs to the chloride channel CLIC family.

Subcellular localisation

Cytoskeleton

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Product protocols

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Target data

In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor (By similarity). Can insert into membranes and form non-selective ion channels almost equally permeable to Na(+), K(+) and Cl(-) (PubMed : 15184393, PubMed : 18028448). Required for normal hearing (PubMed : 24781754). It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed : 15184393, PubMed : 18028448, PubMed : 20335315). Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens (By similarity).
See full target information CLIC5
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