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AB140548

Recombinant Human CNBP protein (His tag N-Terminus)

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Recombinant Human CNBP protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 170 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

RNF163, ZNF9, CNBP, CCHC-type zinc finger nucleic acid binding protein, Cellular nucleic acid-binding protein, Zinc finger protein 9

1 Images
SDS-PAGE - Recombinant Human CNBP protein (His tag N-Terminus) (AB140548)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CNBP protein (His tag N-Terminus) (AB140548)

15% SDS-PAGE analysis ab140548 (3μg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

P62633

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 20% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMSSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA","proteinLength":"Full Length","predictedMolecularWeight":"21 kDa","actualMolecularWeight":null,"aminoAcidEnd":170,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P62633","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab140548 is purified using conventional chromatography techniques.

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General info

Function

Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (PubMed : 2562787). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity).. Isoform 1. Binds G-rich elements in target mRNA coding sequences (PubMed : 28329689). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (PubMed : 28329689).. Isoform 2. Binds to RNA.. Isoform 4. Binds to RNA.. Isoform 5. Binds to RNA.. Isoform 6. Binds to RNA.. Isoform 8. Binds to RNA.

Post-translational modifications

Arginine methylation by PRMT1 in the Arg/Gly-rich region impedes RNA binding.

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Product protocols

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Target data

Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (PubMed : 2562787). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity).. Isoform 1. Binds G-rich elements in target mRNA coding sequences (PubMed : 28329689). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (PubMed : 28329689).. Isoform 2. Binds to RNA.. Isoform 4. Binds to RNA.. Isoform 5. Binds to RNA.. Isoform 6. Binds to RNA.. Isoform 8. Binds to RNA.
See full target information CNBP
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