JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB267916

Recombinant Human COLEC11 protein (Tagged)

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human COLEC11 protein (Tagged) is a Human Full Length protein, in the 26 to 271 aa range, expressed in Mammalian, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

UNQ596/PRO1182, COLEC11, Collectin-11, Collectin kidney protein 1, CL-K1

3 Images
Mass Spectrometry - Recombinant Human COLEC11 protein (Tagged) (AB267916)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human COLEC11 protein (Tagged) (AB267916)

Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of ab267916 indicates that this peptide derived from Mammalian Cell-expressed Homo sapiens (Human) COLEC11.

Mass Spectrometry - Recombinant Human COLEC11 protein (Tagged) (AB267916)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human COLEC11 protein (Tagged) (AB267916)

Based on the SEQUEST from database of Mammalian Cell host and target protein, the LC-MS/MS Analysis result of ab267916 indicates that this peptide derived from Mammalian Cell-expressed Homo sapiens (Human) COLEC11.

SDS-PAGE - Recombinant Human COLEC11 protein (Tagged) (AB267916)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human COLEC11 protein (Tagged) (AB267916)

SDS-PAGE analysis of ab267916 under reducing conditions.

Key facts

Purity

>90% SDS-PAGE

Expression system

Mammalian

Tags

His tag N-Terminus

Applications

Mass Spec, SDS-PAGE

applications

Biologically active

No

Accession

Q9BWP8

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.2 - 7.4 Constituents: PBS, 6% Trehalose

storage-buffer

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"QPAGDDACSVQILVPGLKGDAGEKGDKGAPGRPGRVGPTGEKGDMGDKGQKGSVGRHGKIGPIGSKGEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAANGLMAAYLAQAGLARVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNNAYDEEDCVEMVASGGWNDVACHTTMYFMCEFDKENM","proteinLength":"Full Length","predictedMolecularWeight":"30.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":271,"aminoAcidStart":26,"nature":"Recombinant","expressionSystem":"Mammalian","accessionNumber":"Q9BWP8","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

Specifications

Form

Liquid

Additional notes

nan

style
left-column

General info

Function

Lectin that plays a role in innate immunity, apoptosis and embryogenesis (PubMed : 21258343, PubMed : 23954398, PubMed : 25912189). Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope (PubMed : 25912189). Primarily recognizes the terminal disaccharide of the glycan (PubMed : 25912189). Also recognizes a subset of fucosylated glycans and lipopolysaccharides (PubMed : 17179669, PubMed : 25912189). Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1 (PubMed : 20956340, PubMed : 25912189). Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis (PubMed : 21258343, PubMed : 28301481).

Sequence similarities

Belongs to the COLEC10/COLEC11 family.

style
left-column

Product protocols

style
left-column

Target data

Lectin that plays a role in innate immunity, apoptosis and embryogenesis (PubMed : 21258343, PubMed : 23954398, PubMed : 25912189). Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope (PubMed : 25912189). Primarily recognizes the terminal disaccharide of the glycan (PubMed : 25912189). Also recognizes a subset of fucosylated glycans and lipopolysaccharides (PubMed : 17179669, PubMed : 25912189). Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1 (PubMed : 20956340, PubMed : 25912189). Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis (PubMed : 21258343, PubMed : 28301481).
See full target information COLEC11
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB238585

Anti-COLEC11 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-COLEC11 antibody (AB238585)

  • 0
  • 0
Proteins & Peptides

AB271721

Recombinant human PRMT5 + MEP50 protein (Active)

Functional Studies - Recombinant human PRMT5 + MEP50 protein (Active) (AB271721)

  • 0
  • 0
Proteins & Peptides

AB198661

Recombinant Human WTAP protein

  • 0
  • 0
Proteins & Peptides

AB259412

Recombinant human VEGF 165A protein (Active)

Premium Bioactive

Mass Spectrometry - Recombinant human VEGF 165A protein (Active) (AB259412)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com