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AB183176

Recombinant Human COMMD6 protein

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Recombinant Human COMMD6 protein is a Human Full Length protein, in the 1 to 85 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

MSTP076, COMMD6, COMM domain-containing protein 6

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q7Z4G1

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7 Constituents: 20% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQNFYRQFKEIAAVIETV","proteinLength":"Full Length","predictedMolecularWeight":"12.08 kDa","actualMolecularWeight":null,"aminoAcidEnd":85,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q7Z4G1","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab183176 is purified using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20 mM Tris pH 7.5, 2 mM EDTA.

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General info

Function

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed : 21778237). Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation.

Subcellular localisation

Nucleus

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Product protocols

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Target data

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed : 21778237). Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation.
See full target information COMMD6
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Product promise

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