Recombinant Human Coronin 1a/TACO protein (GST tag N-Terminus)
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Recombinant Human Coronin 1a/TACO protein (GST tag N-Terminus) is a Human Fragment protein, in the 360 to 461 aa range, expressed in Wheat germ, suitable for ELISA, WB.
View Alternative Names
CORO1, CORO1A, Coronin-1A, Coronin-like protein A, Coronin-like protein p57, Tryptophan aspartate-containing coat protein, Clipin-A, TACO
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Coronin 1a/TACO protein (GST tag N-Terminus) (AB161325)
ab161325 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
General info
Function
May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Sequence similarities
Belongs to the WD repeat coronin family.
Post-translational modifications
phosphorylation at Thr-412 by PKC strongly down-regulates the association with actin.. Polyubiquitinated by RNF128 with 'Lys-48'-linked chains, leading to proteasomal degradation.
Subcellular localisation
Cytoskeleton
Target data
Product promise
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