Recombinant Human CPOX protein (His tag N-Terminus)
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Recombinant Human CPOX protein (His tag N-Terminus) is a Human Full Length protein, in the 111 to 454 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
CPO, CPX, CPOX, COX, Coprogen oxidase, Coproporphyrinogenase
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human CPOX protein (His tag N-Terminus) (AB156972)
15% SDS-PAGE analysis of ab156972 (3 µg).
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CPOX converts coproporphyrinogen III into protoporphyrinogen IX playing a role in the heme biosynthetic pathway. As part of the terminal steps in heme production this transformation is important for synthesizing heme an essential component of hemoglobin myoglobin and various cytochromes. CPOX is not part of any larger enzyme complex but interacts with adjacent enzymes in the metabolic pathway to ensure efficient heme synthesis.
Pathways
CPOX functions in the heme biosynthesis pathway. This pathway is vital for the production of heme enabling the synthesis of hemoglobin and electron transport chains. CPOX acts sequentially after coproporphyrinogen III oxidase and before protoporphyrinogen IX oxidase. The enzyme works in concert with proteins such as uroporphyrinogen III synthase (UROS) in earlier steps of the pathway affecting overall heme production efficiency.
Specifications
Form
Liquid
Additional notes
ab156972 is purified using conventional chromatography techniques.
General info
Function
Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX and participates to the sixth step in the heme biosynthetic pathway.
Sequence similarities
Belongs to the aerobic coproporphyrinogen-III oxidase family.
Subcellular localisation
Mitochondrion intermembrane space
Target data
Product promise
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