Recombinant Human CRMP2 protein is a Human Full Length protein, in the 1 to 572 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
M S Y Q G K K N I P R I T S D R L L I K G G K I V N D D Q S F Y A D I Y M E D G L I K Q I G E N L I V P G G V K T I E A H S R M V I P G G I D V H T R F Q M P D Q G M T S A D D F F Q G T K A A L A G G T T M I I D H V V P E P G T S L L A A F D Q W R E W A D S K S C C D Y S L H V D I S E W H K G I Q E E M E A L V K D H G V N S F L V Y M A F K D R F Q L T D C Q I Y E V L S V I R D I G A I A Q V H A E N G D I I A E E Q Q R I L D L G I T G P E G H V L S R P E E V E A E A V N R A I T I A N Q T N C P L Y I T K V M S K S S A E V I A Q A R K K G T V V Y G E P I T A S L G T D G S H Y W S K N W A K A A A F V T S P P L S P D P T T P D F L N S L L S C G D L Q V T G S A H C T F N T A Q K A V G K D N F T L I P E G T N G T E E R M S V I W D K A V V T G K M D E N Q F V A V T S T N A A K V F N L Y P R K G R I A V G S D A D L V I W D P D S V K T I S A K T H N S S L E Y N I F E G M E C R G S P L V V I S Q G K I V L E D G T L H V T E G S G R Y I P R K P F P D F V Y K R I K A R S R L A E L R G V P R G L Y D G P V C E V S V T P K T V T P A S S A K T S P A K Q Q A P P V R N L H Q S G F S L S G A Q I D D N I P R R T T Q R I V A P P G G R A N I T S L G
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes (for recombinant protein) |
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
CRMP2, ULIP2, DPYSL2, Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, N2A3, Unc-33-like phosphoprotein 2, CRMP-2, ULIP-2
Recombinant Human CRMP2 protein is a Human Full Length protein, in the 1 to 572 aa range, expressed in Wheat germ and suitable for SDS-PAGE, ELISA, WB.
pH: 8
Constituents: 0.79% Tris HCl, 0.3% Glutathione
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.
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12.5% SDS-PAGE analysis of ab114269.
Stained with Coomassie Blue.
Blocking and dilution buffer: 5% NFDM /TBST
All lanes: Western blot - Anti-CRMP1 + CRMP2 antibody [EPR7792] (Anti-CRMP1 + CRMP2 antibody [EPR7792] ab129082) at 1/1000 dilution
Lanes 1 and 3: Western blot - Recombinant Human CRMP1 protein (Recombinant Human CRMP1 protein ab202599)
Lanes 2 and 4: Western blot - Recombinant Human CRMP2 protein (ab114269)
All lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) (Goat Anti-Rabbit IgG H&L (HRP) ab97051) at 1/20000 dilution
Exposure time: 3s
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