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AB211317

Recombinant human CST6 protein (His tag N-Terminus)

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Recombinant human CST6 protein (His tag N-Terminus) is a Human Full Length protein, in the 29 to 149 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, FuncS, Mass Spec.

View Alternative Names

Cystatin-M, Cystatin-6, Cystatin-E, CST6

1 Images
SDS-PAGE - Recombinant human CST6 protein (His tag N-Terminus) (AB211317)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant human CST6 protein (His tag N-Terminus) (AB211317)

15% SDS-PAGE analysis of ab211317 (3μg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

FuncS, SDS-PAGE, Mass Spec

applications

Biologically active

Yes

Biological activity

The IC50 value is < 10nM. The inhibitory function of CST6 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25°C.

Accession

Q15828

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Secondary Antibodies

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Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Primary Antibodies

AB201088

Anti-CST6 antibody

Western blot - Anti-CST6 antibody (AB201088)

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Assay Kits

AB277411

Human CST6 ELISA Kit

ELISA - Human CST6 ELISA Kit (AB277411)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMRPQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQQEKLRCDFEVLVVPWQNSSQLLKHNCVQM","proteinLength":"Full Length","predictedMolecularWeight":"15.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":149,"aminoAcidStart":29,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q15828","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Liquid

Additional notes

ab211317 was purified using conventional chromatography techniques.

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General info

Function

High affinity inhibitor for cathepsin L, cathepsin L2 (cathepsin V), and legumain (PubMed : 30425301). Involved in the regulation of epidermal cornification, and hair follicle morphogenesis and maintenance (PubMed : 30425301).

Sequence similarities

Belongs to the cystatin family.

Post-translational modifications

Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor.

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Product protocols

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Target data

High affinity inhibitor for cathepsin L, cathepsin L2 (cathepsin V), and legumain (PubMed : 30425301). Involved in the regulation of epidermal cornification, and hair follicle morphogenesis and maintenance (PubMed : 30425301).
See full target information CST6
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Product promise

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