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AB268396

Recombinant human Cyclin E2 + CDK2 protein (Active)

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Recombinant human Cyclin E2 + CDK2 protein (Active) is a Human Full Length protein, in the 1 to 404 aa range, expressed in Baculovirus infected Sf9 cells, with >90%, suitable for SDS-PAGE, FuncS.

View Alternative Names

G1/S-specific cyclin-E2, CCNE2

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Functional Studies - Recombinant human Cyclin E2 + CDK2 protein (Active) (AB268396)
  • FuncS

Unknown

Functional Studies - Recombinant human Cyclin E2 + CDK2 protein (Active) (AB268396)

The specific activity of ab268396 was 60 nmol/min/min in a kinase assay using histone H1 as substrate.

SDS-PAGE - Recombinant human Cyclin E2 + CDK2 protein (Active) (AB268396)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human Cyclin E2 + CDK2 protein (Active) (AB268396)

SDS-PAGE analysis of ab268396.

Key facts

Purity

>90% SDS-PAGE

Expression system

Baculovirus infected Sf9 cells

Tags

Tag free

Applications

SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

The specific activity of ab268396 was 60 nmol/min/mg in a kinase assay using histone H1 as substrate.

Accession

O96020

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.79% Tris HCl, 0.31% Glutathione, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Proteins co-expressed.
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Sequence info

[{"sequence":"MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":404,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"O96020","tags":[{"tag":"GST","terminus":"N-Terminus"}]},{"sequence":"MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":298,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Baculovirus infected Sf9 cells","accessionNumber":"P24941","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Liquid

Additional notes

Affinity purified.

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General info

Function

Essential for the control of the cell cycle at the late G1 and early S phase.

Sequence similarities

Belongs to the cyclin family. Cyclin E subfamily.

Post-translational modifications

Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway.. Lactylated at Lys-348 (PubMed:36896611). Delactylated by SIRT3 (PubMed:36896611).

Subcellular localisation

Nucleus

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Product protocols

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Target data

Essential for the control of the cell cycle at the late G1 and early S phase.
See full target information Cyclin E2

Additional targets

Cyclin E2
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