Recombinant Human Cyclin H/p34 protein
Be the first to review this product! Submit a review
|
(0 Publication)
Recombinant Human Cyclin H/p34 protein is a Human Full Length protein, in the 1 to 323 aa range, expressed in Baculovirus infected Sf9 cells, with >90%, suitable for WB.
View Alternative Names
Cyclin-H, MO15-associated protein, p34, p37, CCNH
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human Cyclin H/p34 protein (AB174062)
SDS-PAGE showing ab174062
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Specifications
Form
Liquid
Additional notes
Affinity purified.
General info
Function
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Sequence similarities
Belongs to the cyclin family. Cyclin C subfamily.
Subcellular localisation
Nucleus
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com