Recombinant Human CYP2A13 protein (GST tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

CYP2A13 influences the metabolic processing of xenobiotics. It belongs to the cytochrome P450 superfamily which is a group of enzymes essential for drug metabolism and the synthesis of cholesterol steroids and other lipids. While it does not form a complex itself it actively contributes to bioactivation processes that convert chemical compounds into reactive intermediates. This role is important for how the body handles and processes potential toxins or therapeutic drugs.

Pathways

The enzyme plays a notable role in the metabolism of xenobiotics by cytochrome P450. This pathway is key in converting lipophilic compounds into hydrophilic products for easier excretion. CYP2A13 is also involved in the metabolism of nicotine making it a part of the broader nicotine degradation pathway. It shares functional similarities with other cytochrome P450 family members like CYP2A6 which also participates in nicotine metabolism.