Recombinant Human CYP4X1 protein (GST tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

CYP4X1 catalyzes important reactions in the metabolism of fatty acids and other lipid molecules. It acts as part of a broader enzyme system collaborating with other cytochrome P450 enzymes to accomplish these tasks. CYP4X1 facilitates the formation of various eicosanoids which are signaling molecules involved in regulating vascular and cerebral functions. Its activity influences physiological processes including inflammation and vasoconstriction. Understanding its biochemical role helps clarify how the enzymatic functions align with broader metabolic processes.

Pathways

CYP4X1 interacts with eicosanoid biosynthesis and arachidonic acid pathways. It plays a part in the conversion of arachidonic acid to epoxyeicosatrienoic acids (EETs) influencing vascular tone regulation. CYP4X1 works alongside other cytochrome P450 family members such as CYP2C and CYP2J which also contribute to the metabolism of arachidonic acid. Such interactions enhance our comprehension of how these pathways influence vascular homeostasis and neurovascular responses.