Recombinant Human Cytokeratin 5 protein is a Human Full Length protein, in the 1 to 590 aa range, expressed in Wheat germ, with >=80% purity and suitable for SDS-PAGE, ELISA, WB.
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Key facts
- Purity
- >=80%
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- SDS-PAGE, ELISA, WB
- Biologically active
- No
Amino acid sequence
M S R Q S S V S F R S G G S R S F S T A S A I T P S V S R T S F T S V S R S G G G G G G G F G R V S L A G A C G V G G Y G S R S L Y N L G G S K R I S I S T S G G S F R N R F G A G A G G G Y G F G G G A G S G F G F G G G A G G G F G L G G G A G F G G G F G G P G F P V C P P G G I Q E V T V N Q S L L T P L N L Q I D P S I Q R V R T E E R E Q I K T L N N K F A S F I D K V R F L E Q Q N K V L D T K W T L L Q E Q G T K T V R Q N L E P L F E Q Y I N N L R R Q L D S I V G E R G R L D S E L R N M Q D L V E D F K N K Y E D E I N K R T T A E N E F V M L K K D V D A A Y M N K V E L E A K V D A L M D E I N F M K M F F D A E L S Q M Q T H V S D T S V V L S M D N N R N L D L D S I I A E V K A Q Y E E I A N R S R T E A E S W Y Q T K Y E E L Q Q T A G R H G D D L R N T K H E I S E M N R M I Q R L R A E I D N V K K Q C A N L Q N A I A D A E Q R G E L A L K D A R N K L A E L E E A L Q K A K Q D M A R L L R E Y Q E L M N T K L A L D V E I A T Y R K L L E G E E C R L S G E G V G P V N I S V V T G S V S S G Y G S G S G Y G G G L G G G L G G G L G G G L A G G G S G S Y Y S S S S G G V G L S G G L S V G G S G F S A S S G R G L G V G F G S G G G S S S S V K F V S T T S S S R K S F K S
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Associated Products
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Target data
Function
Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity).
Alternative names
58 kDa cytokeratin, Cytokeratin-5, Keratin-5, Type-II keratin Kb5, CK-5, K5, KRT5
Recommended products
Recombinant Human Cytokeratin 5 protein is a Human Full Length protein, in the 1 to 590 aa range, expressed in Wheat germ, with >=80% purity and suitable for SDS-PAGE, ELISA, WB.
Key facts
- Purity
- >=80%
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- SDS-PAGE, ELISA, WB
- Biologically active
- No
- Accession
- P13647-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Sequence info
Amino acid sequence
- M S R Q S S V S F R S G G S R S F S T A S A I T P S V S R T S F T S V S R S G G G G G G G F G R V S L A G A C G V G G Y G S R S L Y N L G G S K R I S I S T S G G S F R N R F G A G A G G G Y G F G G G A G S G F G F G G G A G G G F G L G G G A G F G G G F G G P G F P V C P P G G I Q E V T V N Q S L L T P L N L Q I D P S I Q R V R T E E R E Q I K T L N N K F A S F I D K V R F L E Q Q N K V L D T K W T L L Q E Q G T K T V R Q N L E P L F E Q Y I N N L R R Q L D S I V G E R G R L D S E L R N M Q D L V E D F K N K Y E D E I N K R T T A E N E F V M L K K D V D A A Y M N K V E L E A K V D A L M D E I N F M K M F F D A E L S Q M Q T H V S D T S V V L S M D N N R N L D L D S I I A E V K A Q Y E E I A N R S R T E A E S W Y Q T K Y E E L Q Q T A G R H G D D L R N T K H E I S E M N R M I Q R L R A E I D N V K K Q C A N L Q N A I A D A E Q R G E L A L K D A R N K L A E L E E A L Q K A K Q D M A R L L R E Y Q E L M N T K L A L D V E I A T Y R K L L E G E E C R L S G E G V G P V N I S V V T G S V S S G Y G S G S G Y G G G L G G G L G G G L G G G L A G G G S G S Y Y S S S S G G V G L S G G L S V G G S G F S A S S G R G L G V G F G S G G G S S S S V K F V S T T S S S R K S F K S
- Accession
- P13647
- Protein length
- Full Length
- Predicted molecular weight
- 90.64 kDa
- Amino acids
- 1 to 590
- Nature
- Recombinant
- Tags
- GST tag N-Terminus
Specifications
- Form
- Liquid
- Additional notes
Glutathione Sepharose
General info
- Function
Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity).
- Sequence similarities
Belongs to the intermediate filament family.
- Post-translational modifications
Phosphorylated by CDK1, AURKB and Rho-kinase, phosphorylation is regulated by the cell cycle (By similarity). Thr-24 phosphorylation, mediated by CDK1, peaks during prometaphase or metaphase cells with phosphorylated filamentous structures evident throughout the cytoplasm during early mitosis (By similarity). CDK1 phosphorylates Thr-24 in mitotic cells at the site of injury (By similarity).
Storage
- Shipped at conditions
- Dry Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human Cytokeratin 5 protein (ab132931)
12.5% SDS-PAGE analysis of ab132931 stained with Coomassie Blue
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