Recombinant Human DC-SIGNR protein (Fc Chimera) is a Human Fragment protein, in the 78 to 399 aa range, expressed in HEK 293, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
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Key facts
- Purity
- >90% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- Fc tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
S L S Q E Q S E Q D A I Y Q N L T Q L K A A V G E L S E K S K L Q E I Y Q E L T Q L K A A V G E L P E K S K L Q E I Y Q E L T R L K A A V G E L P E K S K L Q E I Y Q E L T R L K A A V G E L P E K S K L Q E I Y Q E L T R L K A A V G E L P E K S K L Q E I Y Q E L T E L K A A V G E L P E K S K L Q E I Y Q E L T Q L K A A V G E L P D Q S K Q Q Q I Y Q E L T D L K T A F E R L C R H C P K D W T F F Q G N C Y F M S N S Q R N W H D S V T A C Q E V R A Q L V V I K T A E E Q N F L Q L Q T S R S N R F S W M G L S D L N Q E G T W Q W V D G S P L S P S F Q R Y W N S G E P N N S G N E D C A E F S G S G W N D N R C D V D N Y W I C K K P A A C F R D E
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for Ebolavirus. (Microbial infection) Acts as an attachment receptor for Hepatitis C virus. (Microbial infection) Acts as an attachment receptor for HIV-1. (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E. (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5. (Microbial infection) Acts as an attachment receptor for Influenzavirus. (Microbial infection) Acts as an attachment receptor for SARS-CoV. (Microbial infection) Acts as an attachment receptor for West-nile virus. (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus. (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein. (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule.
Alternative names
CD299, CD209L, CD209L1, CLEC4M, C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, DC-SIGNR, DC-SIGN2, L-SIGN
Recommended products
Recombinant Human DC-SIGNR protein (Fc Chimera) is a Human Fragment protein, in the 78 to 399 aa range, expressed in HEK 293, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE.
Key facts
- Purity
- >90% SDS-PAGE
- Endotoxin level
- < 1 EU/µg
- Expression system
- HEK 293 cells
- Tags
- Fc tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q9H2X3-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 7.4
Constituents: 100% PBS
Sequence info
Amino acid sequence
- S L S Q E Q S E Q D A I Y Q N L T Q L K A A V G E L S E K S K L Q E I Y Q E L T Q L K A A V G E L P E K S K L Q E I Y Q E L T R L K A A V G E L P E K S K L Q E I Y Q E L T R L K A A V G E L P E K S K L Q E I Y Q E L T R L K A A V G E L P E K S K L Q E I Y Q E L T E L K A A V G E L P E K S K L Q E I Y Q E L T Q L K A A V G E L P D Q S K Q Q Q I Y Q E L T D L K T A F E R L C R H C P K D W T F F Q G N C Y F M S N S Q R N W H D S V T A C Q E V R A Q L V V I K T A E E Q N F L Q L Q T S R S N R F S W M G L S D L N Q E G T W Q W V D G S P L S P S F Q R Y W N S G E P N N S G N E D C A E F S G S G W N D N R C D V D N Y W I C K K P A A C F R D E
- Accession
- Q9H2X3
- Protein length
- Fragment
- Predicted molecular weight
- 65 kDa
- Amino acids
- 78 to 399
- Nature
- Recombinant
- Tags
- Fc tag N-Terminus
Specifications
- Form
- Lyophilized
General info
- Function
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
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1 product image
SDS-PAGE - Recombinant Human DC-SIGNR protein (Fc Chimera) (ab276295)
SDS-PAGE analysis of ab276295
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