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AB235679

Recombinant Human DCD protein (Tagged)

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Recombinant Human DCD protein (Tagged) is a Human Full Length protein, in the 20 to 110 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

View Alternative Names

AIDD, DSEP, DCD, Dermcidin, Preproteolysin

1 Images
SDS-PAGE - Recombinant Human DCD protein (Tagged) (AB235679)
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Supplier Data

SDS-PAGE - Recombinant Human DCD protein (Tagged) (AB235679)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis with 5% enrichment gel and 15% separation gel of ab235679.

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

6x His tag N-Terminus B2M tag N-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

P81605

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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Complementary Products

Proteins & Peptides

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Native Bovine Collagen protein (FITC)

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Primary Antibodies

AB260043

Anti-Collagen I antibody [EPR22894-89]

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Western blot - Anti-Collagen I antibody [EPR22894-89] (AB260043)

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Primary Antibodies

AB184993

Anti-Collagen III antibody [EPR17673]

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Immunocytochemistry/ Immunofluorescence - Anti-Collagen III antibody [EPR17673] (AB184993)

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Primary Antibodies

AB109725

Anti-Cytokeratin 17 antibody [EP1623] - Cytoskeleton Marker

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 17 antibody [EP1623] - Cytoskeleton Marker (AB109725)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

Protein previously labeled as Dermcidin.
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Sequence info

[{"sequence":"YDPEAASAPGSGNPCHEASAAQKENAGEDPGLARQAPKPRKQRSSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL","proteinLength":"Full Length","predictedMolecularWeight":"23.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":110,"aminoAcidStart":20,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P81605","tags":[{"tag":"6x His","terminus":"N-Terminus"},{"tag":"B2M","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

DCD-1. Found in sweat, has an antimicrobial activity during early bacterial colonization (PubMed : 11694882, PubMed : 23426625). The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes (PubMed : 23426625). Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival (PubMed : 23426625). Highly effective against E.coli, E.faecalis, S.aureus and C.albicans (PubMed : 11694882). Optimal pH and salt concentration resemble the conditions in sweat (PubMed : 11694882). Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues (PubMed : 17448443).. Survival-promoting peptide. Promotes survival of neurons and displays phosphatase activity (PubMed : 9736629). It may bind IgG (PubMed : 9736629).

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Product protocols

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Target data

DCD-1. Found in sweat, has an antimicrobial activity during early bacterial colonization (PubMed : 11694882, PubMed : 23426625). The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes (PubMed : 23426625). Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival (PubMed : 23426625). Highly effective against E.coli, E.faecalis, S.aureus and C.albicans (PubMed : 11694882). Optimal pH and salt concentration resemble the conditions in sweat (PubMed : 11694882). Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues (PubMed : 17448443).. Survival-promoting peptide. Promotes survival of neurons and displays phosphatase activity (PubMed : 9736629). It may bind IgG (PubMed : 9736629).
See full target information DCD
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Product promise

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