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AB85758

Recombinant human DCLK2 protein

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Recombinant human DCLK2 protein is a Human Fragment protein, in the 1 to 690 aa range, expressed in Baculovirus infected Sf9 cells, with >80%, suitable for SDS-PAGE, WB, FuncS.

View Alternative Names

DCAMKL2, DCDC3B, DCK2, DCLK2, Serine/threonine-protein kinase DCLK2, CaMK-like CREB regulatory kinase 2, Doublecortin domain-containing protein 3B, Doublecortin-like and CAM kinase-like 2, Doublecortin-like kinase 2, CL2, CLICK-II, CLICK2

4 Images
Functional Studies - Recombinant human DCLK2 protein (AB85758)
  • FuncS

Supplier Data

Functional Studies - Recombinant human DCLK2 protein (AB85758)

The specific activity of DCLK2 (ab85758) was determined to be 105 nmol /min/mg as per activity assay protocol.

Functional Studies - Recombinant human DCLK2 protein (AB85758)
  • FuncS

Unknown

Functional Studies - Recombinant human DCLK2 protein (AB85758)

The Specific activity of ab85758 was determined to be 94 nmol/min/mg.

SDS-PAGE - Recombinant human DCLK2 protein (AB85758)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human DCLK2 protein (AB85758)

SDS PAGE analysis of ab85758

SDS-PAGE - Recombinant human DCLK2 protein (AB85758)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human DCLK2 protein (AB85758)

SDS-PAGE showing ab85758 at approximately 105kDa.

Key facts

Purity

>80% Densitometry

Expression system

Baculovirus infected Sf9 cells

Tags

Tag free

Applications

WB, SDS-PAGE, FuncS

applications

Biologically active

Yes

Biological activity

The Specific activity of ab85758 was determined to be 94 nmol/min/mg.

Accession

Q8N568

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.79% Tris HCl, 0.00385% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.0038% EGTA, 0.00292% EDTA, 0.00174% PMSF

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

ab204861 (Hsp27 peptide) can be utilized as a substrate for assessing kinase activity

Previously labelled as DCAMKL2.

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Sequence info

[{"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":690,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q8N568","tags":[]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
True
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Specifications

Form

Liquid

Additional notes

Affinity purified.

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General info

Function

Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).

Sequence similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

Post-translational modifications

Autophosphorylated.

Subcellular localisation

Cytoskeleton

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Product protocols

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Target data

Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).
See full target information DCLK2
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