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AB187478

Recombinant Human DCTN6/WS3 protein

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Recombinant Human DCTN6/WS3 protein is a Human Full Length protein, in the 1 to 190 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

WS3, DCTN6, Dynactin subunit 6, Dynactin subunit p27, Protein WS-3

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

O00399

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: 90% PBS, 10% Glycerol (glycerin, glycerine)

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Product details

This product was previously labelled as DCTN6
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITPDTEDPEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKTMKGSSTPVKN","proteinLength":"Full Length","predictedMolecularWeight":"23.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":190,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O00399","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

Additional notes

ab187478 was purified by conventional chromatography techniques.

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General info

Function

Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.

Sequence similarities

Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.

Post-translational modifications

Phosphorylation at Thr-186 by CDK1 during mitotic prometaphase creates a binding site for PLK1 that facilitates its recruitment to kinetochores.

Subcellular localisation

Cytoskeleton

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Product protocols

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Target data

Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
See full target information DCTN6
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Complementary Products

Primary Antibodies

AB197913

Anti-DCTN6/WS3 antibody

Western blot - Anti-DCTN6/WS3 antibody (AB197913)

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Product promise

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