Recombinant Human DECR2/PDCR protein
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Recombinant Human DECR2/PDCR protein is a Human Full Length protein, in the 1 to 292 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
PDCR, SDR17C1, DECR2, pDCR, Short chain dehydrogenase/reductase family 17C member 1
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human DECR2/PDCR protein (AB116178)
15% SDS-PAGE gel analysis of 3 µg ab116178.
Reactivity data
Product details
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
DECR2 facilitates the β-oxidation of unsaturated fatty acids therefore supporting energy production. As part of lipid metabolism it helps to maintain cellular energy balance and influences overall energy homeostasis. This enzyme does not form a complex but interacts with other mitochondrial enzymes to synchronize fatty acid degradation processes allowing cells to utilize stored fats efficiently.
Pathways
DECR2 integrates into the fatty acid oxidation pathway which links to energy metabolism pathways providing substrates for ATP production. This enzyme collaborates closely with other molecules like acyl-CoA dehydrogenases and enoyl-CoA isomerases within these pathways. This collaboration ensures the complete breakdown of unsaturated fatty acids influencing both energy production and mitochondrial function.
Specifications
Form
Liquid
Additional notes
ab116178 was purified using conventional chromatography.
General info
Function
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Sequence similarities
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
Subcellular localisation
Peroxisome
Target data
Complementary Products
Product promise
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