Recombinant Human DGCR6L protein

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

DGCR6L also known as DiGeorge Syndrome Critical Region Gene 6-Like is a protein with a molecular mass of approximately 26 kDa. It acts within cells potentially influencing their structure or signaling processes although its detailed mechanistic role remains subject to further studies. Researchers observe its expression mainly in fetal and adult human tissues with higher levels reported in lymph nodes adult liver heart and skeletal muscle. Its expression pattern suggests that DGCR6L may have essential roles in development and immune function.

Biological function summary

The protein contributes to various cellular processes and might interact with other proteins although it is not part of a well-defined complex. It shares similarities with DGCR6 which implicates it in cellular migration and possibly in neuron-related functions. DGCR6L likely plays a role in early cell development and organization aiding tissue formation and function maintenance across different organs. Scientists believe this protein could be involved in regulatory pathways though specific biological activities require more research.

Pathways

The DGCR6L protein participates in cellular development and signaling pathways. It potentially engages in pathways related to cellular organization and nervous system development due to its similarities with DGCR6. Its relationship with DGCR6 implies DGCR6L might impact pathways that involve neural development impacting proteins associated with development and cellular architecture. By being part of these pathways DGCR6L may have a role in signaling cascades important for organogenesis and cell communication.

The DGCR6L protein has connections to developmental disorders. Its association with DiGeorge Syndrome a condition often linked to defects in chromosome 22 points to possible contributions to phenotypic manifestations of this genetic disorder. The protein's interplay with DGCR6 may influence susceptibility to certain symptoms associated with immune system deficiencies or congenital heart diseases often observed in DiGeorge Syndrome. Additionally DGCR6L might be relevant in exploring therapeutic targets for improving embryonic development outcomes or focusing on immune-related disorders.