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AB105132

Recombinant Human DNAJB6 protein

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Recombinant Human DNAJB6 protein is a Human Full Length protein, in the 1 to 326 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

HSJ2, MRJ, MSJ1, DNAJB6, DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, MSJ-1, HSJ-2

1 Images
SDS-PAGE - Recombinant Human DNAJB6 protein (AB105132)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human DNAJB6 protein (AB105132)

15% SDS-PAGE showing ab105132 (3 μg) at approximately 38.5 kDa.

Key facts

Purity

>85% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

O75190

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 30% Glycerol (glycerin, glycerine), 1.16% Sodium chloride, 0.316% Tris HCl, 0.077% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"ab105132 is purified using conventional chromatography techniques.","proteinLength":"Full Length","predictedMolecularWeight":"38.5 kDa","actualMolecularWeight":null,"aminoAcidEnd":326,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"O75190","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed : 10954706, PubMed : 28233300). Plays an indispensable role in the organization of KRT8/KRT18 filaments (PubMed : 10954706). Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin (PubMed : 11896048, PubMed : 22366786). Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (PubMed : 20159555, PubMed : 22366786). Also reduces cellular toxicity and caspase-3 activity (PubMed : 11896048).. Isoform B. Isoform B but not isoform A inhibits huntingtin aggregation.

Subcellular localisation

Nucleus

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Product protocols

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Target data

Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed : 10954706, PubMed : 28233300). Plays an indispensable role in the organization of KRT8/KRT18 filaments (PubMed : 10954706). Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin (PubMed : 11896048, PubMed : 22366786). Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (PubMed : 20159555, PubMed : 22366786). Also reduces cellular toxicity and caspase-3 activity (PubMed : 11896048).. Isoform B. Isoform B but not isoform A inhibits huntingtin aggregation.
See full target information DNAJB6
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