Recombinant Human DPL protein (His tag N-Terminus)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The term DPL often refers to a protein involved in cellular processes and may also be known as "dpl" or "aa dpl". Its exact molecular mass can vary based on the isoform and the species in which it is found. DPL is expressed in various tissues including the brain liver and heart making it an important target for therapeutic studies in diverse physiological contexts. Researchers investigate this protein to understand better its mechanical roles in maintaining cellular functions.

Biological function summary

DPL participates in cellular signaling and structural integrity. It sometimes acts as part of a larger protein complex facilitating communication and interactions between cells. The molecular interactions with other proteins help maintain cellular homeostasis. The coupling with other cellular components might also contribute to energy metabolism and cytoskeletal organization critical to cell health and function.

Pathways

DPL plays a role in specific signaling pathways like the MAPK/ERK and PI3K/AKT pathways. These pathways are significant for cell proliferation differentiation and survival. DPL interacts with other proteins such as Raf and PI3K enabling these signaling cascades essential for cellular responses to external stimuli. The pathways involving DPL are important for understanding various cellular mechanisms and how they relate to broader biological activities across systems.

DPL has connections to certain conditions including cancer and cardiovascular diseases. Abnormal expression or mutations in DPL can disrupt normal cellular signaling contributing to tumorigenesis and heart dysfunction. In cancer DPL may interact with oncogenes like KRAS affecting tumor growth and spread. In heart disorders alterations in DPL-associated pathways could impact cardiac cell function connecting it to other proteins such as troponin related to heart muscle contraction abnormalities.