Recombinant Human DSCR1L1 protein
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Recombinant Human DSCR1L1 protein is a Human Full Length protein, in the 1 to 197 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
DSCR1L1, ZAKI4, RCAN2, Calcipressin-2, Down syndrome candidate region 1-like 1, Myocyte-enriched calcineurin-interacting protein 2, Regulator of calcineurin 2, Thyroid hormone-responsive protein ZAKI-4, MCIP2
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human DSCR1L1 protein (AB115724)
15% SDS-PAGE analysis of 3 µg ab115724.
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This protein plays an important role in regulating calcium-dependent signaling pathways. Although DSCR1L1 is not typically part of a multiprotein complex it influences pathways through direct and indirect interactions. By inhibiting calcineurin DSCR1L1 limits the dephosphorylation of Nuclear Factor of Activated T-cells (NFAT) proteins which are key transcription factors. This regulation is critical for diverse biological processes including immune response and muscle development.
Pathways
DSCR1L1 modulates the calcineurin-NFAT signaling pathway which is essential for the transduction of calcium signals and the subsequent regulation of gene expression. This protein's interaction with calcineurin affects the transcriptional activity of NFAT proteins which are active in many physiological processes. DSCR1L1 is also connected with the oxidative stress response pathway where it interacts with other proteins that regulate cellular stress responses.
Specifications
Form
Liquid
Additional notes
> 85% by SDS - PAGE. ab115724 is purified by using conventional chromatography techniques.
General info
Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Sequence similarities
Belongs to the RCAN family.
Target data
Complementary Products
Product promise
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