Recombinant Human DUSP26 protein (denatured) is a Human Full Length protein, in the 1 to 211 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
Images
Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
Amino acid sequence
M G S S H H H H H H S S G L V P R G S H M G S M C P G N W L W A S M T F M A R F S R S S S R S P V R T R G T L E E M P T V Q H P F L N V F E L E R L L Y T G K T A C N H A D E V W P G L Y L G D Q D M A N N R R E L R R L G I T H V L N A S H S R W R G T P E A Y E G L G I R Y L G V E A H D S P A F D M S I H F Q T A A D F I H R A L S Q P G G K I L V H C A V G V S R S A T L V L A Y L M L Y H H L T L V E A I K K V K D H R G I I P N R G F L R Q L L A L D R R L R Q G L E A
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application SDS-PAGE | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Alternative names
DUSP24, LDP4, MKP8, NATA1, SKRP3, DUSP26, Dual specificity protein phosphatase 26, Dual specificity phosphatase SKRP3, Low-molecular-mass dual-specificity phosphatase 4, Mitogen-activated protein kinase phosphatase 8, Novel amplified gene in thyroid anaplastic cancer, DSP-4, LDP-4, MAP kinase phosphatase 8, MKP-8
Recommended products
Recombinant Human DUSP26 protein (denatured) is a Human Full Length protein, in the 1 to 211 aa range, expressed in Escherichia coli, with >85% purity and suitable for SDS-PAGE.
Key facts
- Purity
- >85% SDS-PAGE
- Expression system
- Escherichia coli
- Tags
- His tag N-Terminus
- Applications
- SDS-PAGE
- Biologically active
- No
- Accession
- Q9BV47-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 10% Glycerol (glycerin, glycerine), 2.4% Urea, 0.32% Tris HCl
Sequence info
Amino acid sequence
- M G S S H H H H H H S S G L V P R G S H M G S M C P G N W L W A S M T F M A R F S R S S S R S P V R T R G T L E E M P T V Q H P F L N V F E L E R L L Y T G K T A C N H A D E V W P G L Y L G D Q D M A N N R R E L R R L G I T H V L N A S H S R W R G T P E A Y E G L G I R Y L G V E A H D S P A F D M S I H F Q T A A D F I H R A L S Q P G G K I L V H C A V G V S R S A T L V L A Y L M L Y H H L T L V E A I K K V K D H R G I I P N R G F L R Q L L A L D R R L R Q G L E A
- Accession
- Q9BV47
- Protein length
- Full Length
- Predicted molecular weight
- 26.3 kDa
- Amino acids
- 1 to 211
- Nature
- Recombinant
- Tags
- His tag N-Terminus
Specifications
- Form
- Liquid
General info
- Function
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
- Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
- Subcellular localisation
- Nucleus
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human DUSP26 protein (denatured) (ab171697)
15% SDS-PAGE analysis of ab171697 (3 µg).
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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