Recombinant Human DUSP27 protein is a Human Full Length protein, in the 1 to 220 aa range, expressed in Wheat germ and suitable for ELISA, WB.
Images
Key facts
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- ELISA, WB
- Biologically active
- No
Amino acid sequence
M T S G E V K T S L K N A Y S S A K R L S P K M E E E G E E E D Y C T P G A F E L E R L F W K G S P Q Y T H V N E V W P K L Y I G D E A T A L D R Y R L Q K A G F T H V L N A A H G R W N V D T G P D Y Y R D M D I Q Y H G V E A D D L P T F D L S V F F Y P A A A F I D R A L S D D H S K I L V H C V M G R S R S A T L V L A Y L M I H K D M T L V D A I Q Q V A K N R C V L P N R G F L K Q L R E L D K Q L V Q Q R R R S Q R Q D G E E E D G R E L
Reactivity data
| Application | Reactivity | Dilution info | Notes |
|---|---|---|---|
Application ELISA | Reactivity Reacts | Dilution info - | Notes - |
Application WB | Reactivity Reacts | Dilution info - | Notes - |
Target data
Function
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (PubMed:17498703). Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase (By similarity). Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity).
Alternative names
DUPD1, DUSP27, DUSP29, Dual specificity phosphatase 29, Dual specificity phosphatase 27, Dual specificity phosphatase DUPD1
Recommended products
Recombinant Human DUSP27 protein is a Human Full Length protein, in the 1 to 220 aa range, expressed in Wheat germ and suitable for ELISA, WB.
Key facts
- Expression system
- Wheat germ
- Tags
- GST tag N-Terminus
- Applications
- ELISA, WB
- Biologically active
- No
- Accession
- Q68J44-1
- Animal free
- No
- Species
- Human
- Concentration
- Storage buffer
pH: 8
Constituents: 0.79% Tris HCl, 0.31% Glutathione
Sequence info
Amino acid sequence
- M T S G E V K T S L K N A Y S S A K R L S P K M E E E G E E E D Y C T P G A F E L E R L F W K G S P Q Y T H V N E V W P K L Y I G D E A T A L D R Y R L Q K A G F T H V L N A A H G R W N V D T G P D Y Y R D M D I Q Y H G V E A D D L P T F D L S V F F Y P A A A F I D R A L S D D H S K I L V H C V M G R S R S A T L V L A Y L M I H K D M T L V D A I Q Q V A K N R C V L P N R G F L K Q L R E L D K Q L V Q Q R R R S Q R Q D G E E E D G R E L
- Accession
- Q68J44
- Protein length
- Full Length
- Amino acids
- 1 to 220
- Nature
- Recombinant
- Tags
- GST tag N-Terminus
Specifications
- Form
- Liquid
General info
- Function
Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (PubMed:17498703). Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase (By similarity). Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity).
- Sequence similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
- Subcellular localisation
- Nucleus
Storage
- Shipped at conditions
- Dry Ice
- Appropriate short-term storage conditions
- -80°C
- Appropriate long-term storage conditions
- -80°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
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Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
SDS-PAGE - Recombinant Human DUSP27 protein (ab166252)
ab166252 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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