Recombinant Human ELAVL2 protein (His tag N-Terminus)
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Recombinant Human ELAVL2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 346 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.
View Alternative Names
HUB, ELAVL2, ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, Nervous system-specific RNA-binding protein Hel-N1, HuB
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human ELAVL2 protein (His tag N-Terminus) (AB202208)
15% SDS-PAGE analysis of ab202208 (3 μg).
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ELAVL2 modulates the post-transcriptional regulation of mRNA influencing processes like mRNA localization stabilization and translation within neurons. It forms part of ribonucleoprotein complexes that manage the life cycle of mRNAs. Through its interaction with specific mRNA targets ELAVL2 affects the translation of proteins that are essential for synaptic plasticity and neuronal connectivity which are critical processes in maintaining healthy brain function.
Pathways
ELAVL2 integrates into pathways that include the regulation of neuronal mRNA surveillance and synaptic signaling. In these pathways ELAVL2 interacts with related proteins such as ELAVL1 and ELAVL3 which also bind to RNA. These proteins share a common function in maintaining the balance of mRNA levels within neurons. ELAVL2's role in synaptic signaling highlights its involvement in the transmission of information across synapses important for learning and memory.
Specifications
Form
Liquid
Additional notes
ab202208 was purified using conventional chromatography.
General info
Function
RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs (By similarity). Seems to recognize a GAAA motif (By similarity). Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR (By similarity).
Sequence similarities
Belongs to the RRM elav family.
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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