Recombinant Human ENPP5 protein (His tag)

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Researchers propose that ENPP5 contributes to nucleotide metabolism and signaling processes. Although ENPP5 is not directly part of a larger protein complex it functions alongside similar enzymes sharing common substrates and physiological roles. By maintaining balance in the extracellular nucleotide levels ENPP5 can influence processes such as cellular signaling potentially affecting cell growth and differentiation in its primary tissues.

Pathways

ENPP5 activity relates to purine metabolism and the signal transduction pathways that involve nucleotides. One primary pathway where it plays a role is the nucleotide catabolic process interacting indirectly with proteins such as ENPP1 and ENPP2 that manage pyrophosphate and phospholipid metabolism. ENPP5 by breaking down nucleotides influences signal transduction pathways like the P2Y receptor-mediated pathways which are important for various physiological functions.