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AB162830

Recombinant Human EPDR1 protein (GST tag N-Terminus)

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(1 Publication)

Recombinant Human EPDR1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 38 to 224 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

MERP1, UCC1, EPDR1, Mammalian ependymin-related protein 1, MERP-1, Upregulated in colorectal cancer gene 1 protein

1 Images
SDS-PAGE - Recombinant Human EPDR1 protein (GST tag N-Terminus) (AB162830)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human EPDR1 protein (GST tag N-Terminus) (AB162830)

ab162830 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q9UM22

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Primary Antibodies

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Primary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"APRPCQAPQQWEGRQVMYQQSSGRNSRALLSYDGLNQRVRVLDERKALIPCKRLFEYILLYKDGVMFQIDQATKQCSKMTLTQPWDPLDIPQNSTFEDQYSIGGPQEQITVQEWSDRKSARSYETWIGIYTVKDCYPVQETFTINYSVILSTRFFDIQLGIKDPSVFTPPSTCQMAQLEKMSEDCSW","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":224,"aminoAcidStart":38,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9UM22","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

EPDR1 also known as Ependymin-Related 1 is a protein involved in cellular adhesion and signaling. It has an approximate molecular mass of 55 kDa. EPDR1 is expressed in various tissues with significant levels found in the brain and also in some cancerous tissues. The protein plays a role in cellular interaction by mediating cell-cell and cell-matrix adhesion contributing to cellular cohesion and integrity.
Biological function summary

EPDR1 functions in processes of cell adhesion and immune response modulation. It may form complexes with other proteins that help regulate the structural organization of cells within tissue matrices. This modulation is essential for the repair and maintenance of tissue architecture actively influencing how cells respond to environmental changes.

Pathways

EPDR1 is significant in the ECM-receptor interaction pathway and plays a role in cell communication pathways. It interacts with other proteins like integrins which are important in mediating outside-in signaling processes. This interaction facilitates various downstream signaling events that are necessary for maintaining cell and tissue structure.

EPDR1 has been associated with cancer and neurodegenerative diseases. It may influence cancer progression through its impact on cell adhesion potentially affecting metastasis by altering cell motility and detachment. In neurological contexts the relationship with neurodegenerative diseases links to proteins like amyloid-beta where modulation by EPDR1 can affect disease progression by influencing cellular adhesion properties in neural tissues.
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Specifications

Form

Liquid

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General info

Function

Binds anionic lipids and gangliosides at acidic pH.

Sequence similarities

Belongs to the ependymin family.

Post-translational modifications

N-glycosylated; the glycan contains mannose-6-phosphate moieties.

Subcellular localisation

Lysosome lumen

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Product protocols

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Target data

Binds anionic lipids and gangliosides at acidic pH.
See full target information EPDR1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cells 11: PubMed36497009

2022

Aging Fibroblasts Adversely Affect Extracellular Matrix Formation via the Senescent Humoral Factor Ependymin-Related Protein 1.

Applications

Unspecified application

Species

Unspecified reactive species

Kento Takaya,Toru Asou,Kazuo Kishi
View all publications
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Product promise

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