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AB160624

Recombinant Human FAM131B protein (GST tag N-Terminus)

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Recombinant Human FAM131B protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 332 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

KIAA0773, FAM131B, Protein FAM131B

1 Images
SDS-PAGE - Recombinant Human FAM131B protein (GST tag N-Terminus) (AB160624)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human FAM131B protein (GST tag N-Terminus) (AB160624)

ab160624 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q86XD5

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MDSTSSLHGSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMKDHVTKPTAMGQGRVAHMIEWQGWGKTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMSVNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLIASPATGSYLGPAFDDSQPSLHEMGPSQPASGYSALEPPPLLGGDTDWAPGVGAVDLARGPAEEEKRPLAPEEGEDAGCQDLESLSPREDPEMSTTLSRKVSDVTSSGVQSFDEEEGEANN","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":332,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q86XD5","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM131B also known as Family with Sequence Similarity 131 Member B is a 33 kDa protein. It is expressed in various tissues including the heart liver and skeletal muscles. The protein is intracellular and appears to play a role in cellular processes by interacting with other proteins involved in signaling pathways.
Biological function summary

The FAM131B protein contributes to cellular growth and regulation. It can form complexes with other cellular proteins to modulate their activity. This function suggests that FAM131B might have a hand in orchestrating cellular responses to environmental stimuli assisting cells to adapt and respond effectively.

Pathways

FAM131B is involved in protein kinase signaling and gene expression regulation. It interacts with proteins such as RET and ELK1 which are essential for signal transduction and transcription regulation. This participation indicates that FAM131B acts as a mediator in pathways that influence cellular differentiation and development.

Studies have shown the involvement of FAM131B in certain types of cancer especially thyroid carcinoma. The protein forms a fusion with RET to create the RET/PTC rearrangement which leads to tumor development. In fibrolamellar hepatocellular carcinoma it associates with DNAJB1 suggesting a role in tumorigenesis by contributing to abnormal gene regulation.
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Specifications

Form

Liquid

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General info

Sequence similarities

Belongs to the FAM131 family.

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Product protocols

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Target data

See full target information FAM131B
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Product promise

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