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AB165954

Recombinant Human FAM13C1 protein

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Recombinant Human FAM13C1 protein is a Human Full Length protein, in the 1 to 585 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

FAM13C1, FAM13C, Protein FAM13C

1 Images
SDS-PAGE - Recombinant Human FAM13C1 protein (AB165954)
  • SDS-PAGE

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SDS-PAGE - Recombinant Human FAM13C1 protein (AB165954)

ab165954 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q8NE31

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRHSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":585,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q8NE31","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM13C1 also known as Family with Sequence Similarity 13 Member C1 is a protein with a molecular mass of approximately 115 kDa. This protein is primarily expressed in the pancreas and to some extent in adipose tissue. FAM13C1 resides in the cytoplasm and interacts with components of the cytoskeleton indicating a role in cellular architecture and signaling.
Biological function summary

The protein FAM13C1 is involved in regulating glucose metabolism and insulin signaling. It forms part of a dynamic protein complex that modulates the function of metabolic pathways. Research suggests it influences the activity of enzymes linked to lipid metabolism which can affect energy storage and usage in cells. This function positions FAM13C1 as an important modulator of metabolic processes.

Pathways

FAM13C1 plays a role in the insulin signaling pathway and the PI3K-Akt signaling pathway. Its function in these pathways ties it closely with proteins like PI3K and AKT which are critical for cellular growth metabolism and survival. FAM13C1’s interaction with these pathways highlights its contribution to both signaling and metabolic regulation in cells.

FAM13C1 has been associated with type 2 diabetes and obesity. Alterations in this protein's function or expression may disrupt normal insulin signaling potentially leading to insulin resistance. Such disruption links FAM13C1 with proteins like IRS1 which also play roles in insulin signaling and metabolic homeostasis. This connection highlights FAM13C1's significance in metabolic disorders.
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Specifications

Form

Liquid

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General info

Sequence similarities

Belongs to the FAM13 family.

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Product protocols

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Target data

See full target information FAM13C
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