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AB276667

Recombinant Human FAM150A protein (Fc Chimera)

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Recombinant Human FAM150A protein (Fc Chimera) is a Human Full Length protein, in the 1 to 129 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

View Alternative Names

FAM150A, UNQ9433/PRO34745, ALKAL1, ALK and LTK ligand 1, Augmentor beta, AUG-beta

1 Images
SDS-PAGE - Recombinant Human FAM150A protein (Fc Chimera) (AB276667)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human FAM150A protein (Fc Chimera) (AB276667)

SDS-PAGE analysis of ab276667

Key facts

Purity

>90% SDS-PAGE

Endotoxin level

< 1 EU/µg

Expression system

HEK 293 cells

Tags

Fc tag C-Terminus

Applications

SDS-PAGE

applications

Biologically active

No

Accession

Q6UXT8

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 7.4 Constituents: PBS

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

Sequence info

[{"sequence":"MRPLKPGAPLPALFLLALALSPHGAHGRPRGRRGARVTDKEPKPLLFLPAAGAGRTPSGSRSAEIFPRDSNLKDKFIKHFTGPVTFSPECSKHFHRLYYNTRECSTPAYYKRCARLLTRLAVSPLCSQT","proteinLength":"Full Length","predictedMolecularWeight":"14 kDa","actualMolecularWeight":null,"aminoAcidEnd":129,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6UXT8","tags":[{"tag":"Fc","terminus":"C-Terminus"}]}]

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM150A also known as Protein C6orf223 is a protein that participates in cellular processes. The molecular mass of FAM150A reaches about 28 kDa. It is notably expressed in tissues such as the brain and reproductive organs. Insight into its expression assists in understanding its mechanical roles within the body.
Biological function summary

FAM150A engages in a variety of essential cellular functions. It does not appear to form part of any larger protein complex but its function is integral to cellular signaling. FAM150A contributes significantly to communication processes between cells influencing cellular responses and adaptations in specific tissue environments.

Pathways

FAM150A plays roles in signal transduction processes. It integrates into pathways like the AKT signaling pathway influencing cellular growth and survival. FAM150A has some interaction with proteins such as the receptor Tyrosine kinase. These interactions mark its importance in maintaining cellular integrity and regulation.

FAM150A has connections to certain neurological disorders and cancer. Abnormal expression or mutation of FAM150A can correlate with the development of glioblastomas a type of brain cancer. Another protein EGFR (epidermal growth factor receptor) interacts with FAM150A within these diseased states potentially affecting disease progression and cellular behavior. Understanding these relationships guides research towards potential therapeutic interventions.

Specifications

Form

Lyophilized

General info

Function

Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation (PubMed : 25331893, PubMed : 26418745, PubMed : 26630010, PubMed : 34646012, PubMed : 34819673). Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation (PubMed : 34646012, PubMed : 34819673). In contrast to ALKAL2, does not act as a potent physiological ligand for ALK (PubMed : 26418745, PubMed : 34646012).

Sequence similarities

Belongs to the ALKAL family.

Product protocols

Target data

Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation (PubMed : 25331893, PubMed : 26418745, PubMed : 26630010, PubMed : 34646012, PubMed : 34819673). Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation (PubMed : 34646012, PubMed : 34819673). In contrast to ALKAL2, does not act as a potent physiological ligand for ALK (PubMed : 26418745, PubMed : 34646012).
See full target information ALKAL1

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