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AB167861

Recombinant Human FAM84A protein

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Recombinant Human FAM84A protein is a Human Full Length protein, in the 1 to 292 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

FAM84A, NSE1, LRATD1, Protein LRATD1, LRAT domain-containing 1, Neurologic sensory protein 1, Protein FAM84A

1 Images
SDS-PAGE - Recombinant Human FAM84A protein (AB167861)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human FAM84A protein (AB167861)

15% SDS-PAGE of 3µg ab167861.

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q96KN4

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDDEEDLDERGQPDKFGVKAPPGCTPCPESPSRHHHHLLHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHLHQGEIRQDSLYEAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLGENKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE","proteinLength":"Full Length","predictedMolecularWeight":"34.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":292,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q96KN4","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FAM84A also known as Family with Sequence Similarity 84 Member A is a protein that plays a role in specific mechanical functions within cells. It has a molecular mass of approximately 24 kDa. This protein is expressed in several tissues with higher expression levels seen in certain carcinoma cell lines. It is frequently found in epithelial tissues indicating its potential involvement in various cellular processes related to these locations.
Biological function summary

Research indicates that FAM84A influences cellular proliferation and migration contributing to normal cell growth and possibly carcinogenic processes. This protein does not associate with any well-defined complex but seems to perform its functions independently or in collaboration with other binding partners yet to be identified. Its role suggests that FAM84A may be important in maintaining cellular architecture and promoting cellular movement especially within epithelial environments.

Pathways

Current studies suggest that FAM84A interacts with cellular pathways associated with cell cycle progression and cancer metastasis. These pathways regulate cell division and expansion contributing to the spread of cancerous cells. FAM84A also shows potential associations with signaling molecules that manage cell motility such as cadherins although direct links in these pathways need more exploration.

FAM84A has been linked to cancer particularly colorectal cancer and prostate cancer. Its upregulation correlates with tumor aggressiveness highlighting its potential as a biomarker for these malignancies. FAM84A also shows interactions with proteins such as p53 which is central to the regulation of cell cycle and apoptosis further supporting its relevance in cancer pathophysiology. Understanding these associations helps in exploring therapeutic approaches targeting FAM84A in certain cancers.
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Specifications

Form

Liquid

Additional notes

ab167861 was purified using conventional chromatography techniques.

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General info

Function

May play a role in cell morphology and motility.

Sequence similarities

Belongs to the LRATD family.

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Product protocols

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Target data

May play a role in cell morphology and motility.
See full target information LRATD1
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Complementary Products

Primary Antibodies

AB126938

Anti-FAM84A antibody

Immunocytochemistry/ Immunofluorescence - Anti-FAM84A antibody (AB126938)

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