Recombinant Human FCRL2 protein (His tag)
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Recombinant Human FCRL2 protein (His tag) is a Human Fragment protein, in the 1 to 395 aa range, expressed in HEK 293 cells, with >90%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.
View Alternative Names
CD307b, FCRH2, IFGP4, IRTA4, SPAP1, UNQ9236/PRO31998, FCRL2, Fc receptor-like protein 2, FcR-like protein 2, FcRL2, Fc receptor homolog 2, IFGP family protein 4, Immunoglobulin receptor translocation-associated protein 4, SH2 domain-containing phosphatase anchor protein 1, FcRH2
- SDS-PAGE
Supplier Data
SDS-PAGE - Recombinant Human FCRL2 protein (His tag) (AB276705)
SDS-PAGE analysis of ab276705
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
FCRL2 modulates signaling in B cells partaking in immune regulation. It participates in the regulatory networks that adjust B-cell function and differentiation but it does not form any known complex with other proteins. The protein has a structural similarity to classical Fc receptors that suggests a modulatory role in immune response. Researchers consider FCRL2 significant in altering B cell receptor signaling though the exact ligands remain under active investigation.
Pathways
The protein FCRL2 integrates into immune signaling pathways such as the B cell receptor (BCR) signaling pathway. This pathway plays a direct role in B cell activation and antibody production. FCRL2 interacts with other FCRLS members in such pathways to maintain immune homeostasis. The extent of its integration implies a fine-tuning of B cell functions and links to Fcγ receptors indicating a shared regulatory network in pathways.
Specifications
Form
Lyophilized
General info
Function
May have an regulatory role in normal and neoplastic B cell development.
Post-translational modifications
Isoform 2 is N- and O-glycosylated, and phosphorylated.
Target data
Complementary Products
![Western blot - Anti-FCRL2 antibody [EPR16122] (AB197897)](https://content.abcam.com/products/images/fcrl2-antibody-epr16122-ab197897--western-blot-img84956.jpg)
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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