Recombinant Human FGF9/GAF Protein
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Recombinant Human FGF9/GAF Protein is a Human Full Length protein, in the 4 to 208 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for Mass Spec, HPLC.
View Alternative Names
Fibroblast growth factor 9, FGF-9, Glia-activating factor, Heparin-binding growth factor 9, GAF, HBGF-9, FGF9
- Mass Spec
Lab
Mass Spectrometry - Recombinant Human FGF9/GAF Protein (AB315081)
Mass determination by ESI-TOF. Predicted MW is 23200 Da (+/- 10 Da by ESI-TOF). Observed MW is 23200.
- HPLC
Lab
HPLC - Recombinant Human FGF9/GAF Protein (AB315081)
HPLC analysis of ab315081
Reactivity data
Sequence info
Properties and storage information
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
FGF9 contributes to important processes in the development and maintenance of several tissues. It is not known to be part of a larger complex. FGF9 regulates cellular activities such as proliferation and differentiation through its interaction with specific receptors on the cell surface. Its role is significant in skeletal and nervous system development where it ensures proper maturation and function of these systems.
Pathways
The FGF9 protein participates in the MAPK/ERK and PI3K/AKT signaling pathways. These pathways are important for cell survival proliferation and differentiation. FGF9 interacts closely with other fibroblast growth factors such as FGF2 to ensure effective signaling cascades. These interactions affect various cellular responses and contribute to the normal development of multiple organ systems.
Specifications
Form
Lyophilized
General info
Function
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
Sequence similarities
Belongs to the heparin-binding growth factors family.
Post-translational modifications
Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step.. N-glycosylated.
Product protocols
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Target data
Product promise
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