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AB158426

Recombinant Human Ficolin 2 protein (GST tag N-Terminus)

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Recombinant Human Ficolin 2 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 313 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

FCNL, FCN2, Ficolin-2, 37 kDa elastin-binding protein, Collagen/fibrinogen domain-containing protein 2, Ficolin-B, Ficolin-beta, Hucolin, L-ficolin, Serum lectin p35, EBP-37

1 Images
SDS-PAGE - Recombinant Human Ficolin 2 protein (GST tag N-Terminus) (AB158426)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Ficolin 2 protein (GST tag N-Terminus) (AB158426)

ab158426 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q15485

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Complementary Products

Proteins & Peptides

AB151947

Recombinant Human Mannan Binding Lectin/MBL protein

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Primary Antibodies

AB190834

Anti-MBL1+MBL2 antibody [EPR18381-156]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MBL1+MBL2 antibody [EPR18381-156] (AB190834)

  • 0
  • 0
Proteins & Peptides

AB276340

Recombinant Human FCN1/M-Ficolin protein (His tag)

SDS-PAGE - Recombinant Human FCN1/M-Ficolin protein (His tag) (AB276340)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":313,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q15485","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Specifications

Form

Liquid

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General info

Function

Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system (PubMed : 10679061, PubMed : 14707097, PubMed : 15804047, PubMed : 17215869, PubMed : 25344472, PubMed : 8576206). Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway (PubMed : 14707097). Specifically binds N-Acetylglucosamine (GlcNAc), as well as phosphocholine and lipoteichoic acid moieties on the surface of pathogens (PubMed : 14707097, PubMed : 17215869, PubMed : 25344472, PubMed : 8576206). Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect (PubMed : 8576206).

Sequence similarities

Belongs to the ficolin lectin family.

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Product protocols

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Target data

Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system (PubMed : 10679061, PubMed : 14707097, PubMed : 15804047, PubMed : 17215869, PubMed : 25344472, PubMed : 8576206). Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway (PubMed : 14707097). Specifically binds N-Acetylglucosamine (GlcNAc), as well as phosphocholine and lipoteichoic acid moieties on the surface of pathogens (PubMed : 14707097, PubMed : 17215869, PubMed : 25344472, PubMed : 8576206). Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect (PubMed : 8576206).
See full target information FCN2
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Product promise

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