JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB158453

Recombinant Human Filamin C protein

Be the first to review this product! Submit a review

|

(0 Publication)

Recombinant Human Filamin C protein is a Human Fragment protein, in the 2606 to 2705 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

ABPL, FLN2, FLNC, Filamin-C, FLN-C, FLNc, ABP-280-like protein, ABP-L, Actin-binding-like protein, Filamin-2, Gamma-filamin

1 Images
SDS-PAGE - Recombinant Human Filamin C protein (AB158453)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Filamin C protein (AB158453)

ab158453 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

WB, ELISA

applications

Biologically active

No

Accession

Q14315

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column
style
left-column

Sequence info

[{"sequence":"SSIPKFSSDASKVVTRGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKEKGDYILIVKWGDESVPGSPFKVKVP","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":2705,"aminoAcidStart":2606,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q14315","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
style
left-column

Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
style
left-column
style
left-column

Specifications

Form

Liquid

style
left-column

General info

Function

Muscle-specific filamin, which plays a central role in sarcomere assembly and organization (PubMed : 34405687). Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events (By similarity).

Sequence similarities

Belongs to the filamin family.

Post-translational modifications

Ubiquitinated by FBXL22, leading to proteasomal degradation.

Subcellular localisation

Cytoskeleton

style
left-column

Product protocols

style
left-column

Target data

Muscle-specific filamin, which plays a central role in sarcomere assembly and organization (PubMed : 34405687). Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events (By similarity).
See full target information FLNC
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB180941

Anti-Filamin C antibody [EPR14498(B)]

RabMAb|Recombinant

Western blot - Anti-Filamin C antibody [EPR14498(B)] (AB180941)

  • 5
  • 2
Assay Kits

AB207196

AP1 (c-Fos/FosB/Fra1/c-Jun/JunD) Transcription Factor Assay Kit (Colorimetric)

Functional Studies - AP1 (c-Fos/FosB/Fra1/c-Jun/JunD) Transcription Factor Assay Kit (Colorimetric) (AB207196)

  • 0
  • 0
Primary Antibodies

AB271180

Rabbit monoclonal [EPR24334-118] to SARS-CoV-2 nucleocapsid protein

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Rabbit monoclonal [EPR24334-118] to SARS-CoV-2 nucleocapsid protein (AB271180)

  • 5
  • 4
Assay Kits

AB219942

Cell Plasma Membrane Staining Kit - Deep Red Fluorescence - Cytopainter

Fluorescence Microscopy - Cell Plasma Membrane Staining Kit - Deep Red Fluorescence - Cytopainter (AB219942)

  • 5
  • 2

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com