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AB165727

Recombinant Human FITM1 protein (GST tag N-Terminus)

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Recombinant Human FITM1 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 292 aa range, expressed in Wheat germ, suitable for ELISA, WB.

View Alternative Names

FIT1, FITM1, Fat storage-inducing transmembrane protein 1, Fat-inducing protein 1

1 Images
SDS-PAGE - Recombinant Human FITM1 protein (GST tag N-Terminus) (AB165727)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human FITM1 protein (GST tag N-Terminus) (AB165727)

ab165727 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

Expression system

Wheat germ

Tags

GST tag N-Terminus

Applications

ELISA, WB

applications

Biologically active

No

Accession

A5D6W6

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MERGPVVGAGLGAGARIQALLGCLLKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVNPRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLATRRVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRRSCLAAGHQWRGYTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPLRLVFLLNVLLLGLWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGSPGHGLFPRPHSSRKHN","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":292,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"A5D6W6","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Dry Ice
Appropriate short-term storage conditions
-80°C
Appropriate long-term storage conditions
-80°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FITM1 also known as Fat Storage-Inducing Transmembrane Protein 1 functions as a lipid droplet protein involved in lipid storage. This protein identifies in mammals with a sequence mass around 29 kDa. It expresses heavily in adipose tissues and to a lesser extent in liver and muscle tissues. FITM1 plays an essential role in regulating lipid droplet formation within these tissues.
Biological function summary

FITM1 facilitates the storage of neutral lipids within cells contributing to overall lipid metabolism. It acts as part of a molecular complex that anchors triglycerides within lipid droplets enabling efficient lipid storage. Through this mechanism FITM1 participates in maintaining cellular lipid balance reflecting its significance in fat storage physiology.

Pathways

FITM1 integrates within metabolic pathways associated with lipid processing and energy homeostasis. Two important pathways include the lipid metabolic pathway and the insulin signaling pathway. FITM1 operates alongside proteins like FITM2 and perilipin where they coordinate to manage lipid droplet dynamics thereby influencing cellular energy metabolism.

FITM1 influences the development of metabolic syndromes such as obesity and non-alcoholic fatty liver disease (NAFLD). Dysregulation of FITM1 affects lipid storage capacity linking it to these conditions. FITM1 connects with proteins involved in these disorders including adiponectin and leptin which play significant roles in energy metabolism and homeostasis.
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Specifications

Form

Liquid

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General info

Function

Plays an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity) (PubMed : 18160536). Directly binds to diacylglycerol (DAGs) and triacylglycerol (By similarity).

Sequence similarities

Belongs to the FIT family. FIT1 subfamily.

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Product protocols

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Target data

Plays an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity) (PubMed : 18160536). Directly binds to diacylglycerol (DAGs) and triacylglycerol (By similarity).
See full target information FITM1
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Product promise

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