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AB156725

Recombinant Human FLJ11506 protein (His tag N-Terminus)

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Recombinant Human FLJ11506 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 315 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

View Alternative Names

Alpha- and gamma-adaptin-binding protein p34, AAGAB

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SDS-PAGE - Recombinant Human FLJ11506 protein (His tag N-Terminus) (AB156725)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human FLJ11506 protein (His tag N-Terminus) (AB156725)

15% SDS-PAGE analysis of ab156725 (3μg).

Key facts

Purity

>90% SDS-PAGE

Expression system

Escherichia coli

Tags

His tag N-Terminus

Applications

SDS-PAGE, Mass Spec

applications

Biologically active

No

Accession

Q6PD74

Animal free

No

Carrier free

No

Species

Human

Storage buffer

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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Sequence info

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMAAGVPCALVTSCSSVFSGDQLVQHILGTEDLIVEVTSNDAVRFYPWTIDNKYYSADINLCVVPNKFLVTAEIAESVQAFVVYFDSTQKSGLDSVSSWLPLAKAWLPEVMILVCDRVSEDGINRQKAQEWCIKHGFELVELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGSADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDVENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDEEH","proteinLength":"Full Length","predictedMolecularWeight":"36.7 kDa","actualMolecularWeight":null,"aminoAcidEnd":315,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q6PD74","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
False
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FLJ11506 also known as C1orf170 is a protein whose function has not been fully established but it plays a role in certain cellular processes. FLJ11506 has an approximate mass of 48 kDa. It is expressed in various tissues showing higher expression levels in certain parts of the brain and other specific organs. Researchers have yet to fully elucidate its mechanical function but it likely has intracellular roles given its expression pattern.
Biological function summary

FLJ11506 may be involved in maintaining cellular functions through its interaction with other proteins. While not confirmed as part of a larger complex its expression profile suggests an involvement in neurological functions. FLJ11506 could influence pathways that manage cellular signaling and communication possibly impacting cell growth or differentiation processes.

Pathways

FLJ11506 may participate in signal transduction mechanisms that affect brain physiology. Although direct pathway associations are not well characterized it is speculated to interact with signaling pathways linked to kinases which are fundamental in regulating cellular activities. Proteins such as MAPKs may have related signaling routes with FLJ11506 highlighting potential roles in neuronal signaling events.

Scientists are investigating FLJ11506 for potential links to neurological conditions such as Alzheimer's disease or Parkinson's disease. Its expression in brain tissues points to a possible involvement in conditions characterized by neurodegeneration. While no direct connections with disease-causing proteins like tau or alpha-synuclein are confirmed there is interest in how FLJ11506's function or dysfunction may influence such disorders. Further studies are necessary to clarify these relationships.
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Specifications

Form

Liquid

Additional notes

ab156725 is purified by using conventional chromatography techniques (anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA).

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General info

Function

May be involved in endocytic recycling of growth factor receptors such as EGFR.

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Product protocols

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Target data

May be involved in endocytic recycling of growth factor receptors such as EGFR.
See full target information AAGAB
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Complementary Products

Primary Antibodies

AB241294

Anti-FLJ11506 antibody

Immunoprecipitation - Anti-FLJ11506 antibody (AB241294)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB137383

Anti-Carma 3 antibody

Western blot - Anti-Carma 3 antibody (AB137383)

  • 0
  • 0
Primary Antibodies

AB218165

Anti-PPP2R3A antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPP2R3A antibody (AB218165)

  • 0
  • 0

Product promise

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